Loading Events

« All Events

Keenan International Lecture:” Strategies to Promote Cancer Nanomedicine Performance and Clinical Translation” presented by Prof. Dr. Dr. Twan Lammers

November 20 @ 1:00 pm - 2:00 pm

We are pleased to invite you to the upcoming Keenan International Lecture, featuring Dr. Prof. Twan Lammers, who will present “Strategies to Promote Cancer Nanomedicine Performance and Clinical Translation.

Date: November 20, 2024
Time: 1:00 – 2:00 PM (EST)
Location: Zoom

Abstract: Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules more ef-fectively and more selectively to pathological sites, and by attenuating their accumulation in healthy organs and tissues, nanomedicines assist in improving the balance between (chemo)therapy efficacy and toxicity. The tumor accumulation of nanomedicines is traditionally ascribed to the EPR effect, which is highly variable, both in animal models and in patients. To address issues associated with tumor targeting heterogeneity, and to advance cancer nanomedicine clinical translation, we are working on systems and strategies to monitor and modulate tumor-targeted drug delivery. In the present lecture, several of these strategies will be highlighted, including image-guided interventions to prime tumor blood vessels and the microenvironment, as well as the use of imaging and tumor tissue biomarkers for patient stratification. These efforts help to establish rational and realistic ways for-ward towards promoting the performance and clinical translation of cancer nanomedicines.

Biosketch: Twan Lammers obtained a D.Sc. in Radiation Oncology from Heidelberg University in 2008 and a Ph.D. in Pharmaceutical Technology from Utrecht University in 2009. In the same year, he started the Nanomed-icine and Theranostics group at RWTH Aachen University. In 2014, he was promoted to full professor of medi-cine at RWTH Aachen University Clinic. His group aims to individualize and improve disease treatment by com-bining drug targeting with imaging. To this end, image-guided (theranostic) drug delivery systems are being de-veloped, as well as materials and methods to monitor tumor growth, angiogenesis, inflammation, fibrosis and metastasis. He has received multiple scholarships and awards, including ERC starting, consolidator and proof-of-concept grants, the CRS Young Investigator Award, the Adritelf International Award, the Belgian Society for Pharmaceutical Sciences International Award, and the JNB Trailblazer Award. He served as the president of the Controlled Release Society in 2023-2024, and he has been a council member of the European Society for Mo-lecular Imaging for almost 10 years. He is a member of the editorial board of 10 journals, and acts as associate editor for JCR, DDTR and MIB. Since 2019, he is included in the Clarivate Analytics list of Highly Cited Research-ers.

Details

Date:
November 20
Time:
1:00 pm - 2:00 pm
Website:
https://ca01web.zoom.us/j/61594077375?pwd=uSKjyiZt0dbrUk6aSx2ROTmji1yU5s.1

Venue

Virtual