Andreas Laupacis


Affiliate Scientist

Research Programs


Please note: Dr. Laupacis is not taking any summer students.

I have a longstanding  interest in clinical epidemiology,  health services research, health policy and  patient involvement in research and health care. I was the founder of Healthy Debate and am currently Editor in Chief of the Canadian Medical Association Journal.


Recent Publications

  1. Persaud, N, Azarpazhooh, A, Keown-Stoneman, C, Birken, CS, Isaranuwatchai, W, Maguire, JL et al.. Xylitol for the prevention of acute otitis media episodes in children aged 1-5 years: a randomised controlled trial. Arch Dis Child. 2024;109 (2):121-124. doi: 10.1136/archdischild-2023-325565. PubMed PMID:37890960 PubMed Central PMC10850643.
  2. Shickh, S, Mighton, C, Clausen, M, Kodida, R, Adi-Wauran, E, Hirjikaka, D et al.. "I don't need any more unknowns hanging over my head": Views of patients with cancer on variants of uncertain significance and low/moderate risk results from genomic sequencing. Genet Med. 2023;25 (12):100960. doi: 10.1016/j.gim.2023.100960. PubMed PMID:37577963 .
  3. Persaud, N, Bedard, M, Boozary, A, Glazier, RH, Gomes, T, Hwang, SW et al.. Effect of Free Medicine Distribution on Health Care Costs in Canada Over 3 Years: A Secondary Analysis of the CLEAN Meds Randomized Clinical Trial. JAMA Health Forum. 2023;4 (5):e231127. doi: 10.1001/jamahealthforum.2023.1127. PubMed PMID:37234014 PubMed Central PMC10220517.
  4. Kodida, R, Reble, E, Clausen, M, Shickh, S, Mighton, C, Sam, J et al.. A model for the return and referral of all clinically significant secondary findings of genomic sequencing. J Med Genet. 2023;60 (8):733-739. doi: 10.1136/jmg-2022-109091. PubMed PMID:37217257 .
  5. Shickh, S, Sebastian, A, Clausen, M, Mighton, C, Elser, C, Eisen, A et al.. Great expectations: patients' preferences for clinically significant results from genomic sequencing. Hum Genet. 2023;142 (4):553-562. doi: 10.1007/s00439-023-02543-3. PubMed PMID:36943453 .
  6. Chin-Yee, N, Gomes, T, Tanuseputro, P, Talarico, R, Laupacis, A. Anticoagulant use and associated outcomes in older patients receiving home palliative care: a retrospective cohort study. CMAJ. 2022;194 (35):E1198-E1208. doi: 10.1503/cmaj.220919. PubMed PMID:36096505 PubMed Central PMC9477253.
  7. Shickh, S, Mighton, C, Clausen, M, Adi-Wauran, E, Hirjikaka, D, Kodida, R et al.. "Doctors shouldn't have to cheat the system": Clinicians' real-world experiences of the utility of genomic sequencing. Genet Med. 2022;24 (9):1888-1898. doi: 10.1016/j.gim.2022.04.024. PubMed PMID:35612591 .
  8. Fuller, A, Siddiqi, A, Shahidi, FV, Anderson, LN, Hildebrand, V, Keown-Stoneman, CDG et al.. Understanding income-related differences in distribution of child growth, behaviour and development using a cross-sectional sample of a clinical cohort study. BMJ Open. 2022;12 (2):e056991. doi: 10.1136/bmjopen-2021-056991. PubMed PMID:35168982 PubMed Central PMC8852748.
  9. Bayoumi, A, Laupacis, A. Outdated criteria for drug plan reimbursement obstruct evidence-based care. CMAJ. 2021;193 (40):E1573-E1574. doi: 10.1503/cmaj.211617. PubMed PMID:35040803 PubMed Central PMC8568076.
  10. Bayoumi, A, Laupacis, A. [Not Available]. CMAJ. 2021;193 (47):E1826-E1827. doi: 10.1503/cmaj.211617-f. PubMed PMID:34844946 PubMed Central PMC8654894.
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Affiliations & Other Activities

  • Adjunct Professor, Department of Medicine, Faculty of Medicine, University of Toronto
  • Professor, Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto
  • Editor in Chief, Canadian Medical Association Journal
  • Senior Fellow, Massey College in the University of Toronto
  • Clinical Specialty: general internal medicine, with a special interest in palliative care (retired)