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Charles de Mestral

MDCM, FRCSC, PhD

Scientist

Email: Charles.deMestral@unityhealth.to
Tel: 416-864-5459
Twitter: @vasc_surg

Research Programs

Biography

Dr. Charles de Mestral is a vascular surgeon at St. Michael’s Hospital and a Surgeon-Scientist in the Department of Surgery of the University of Toronto. He conducts research on clinical effectiveness, as well as the provision, quality and costs of surgical care.  His primary research focus is amputation prevention in people with diabetes and peripheral artery disease. His work is based out of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and ICES.

Please note: Dr. de Mestral is no longer accepting summer students.

 

Recent Publications

  1. Muaddi, H, Lovrics, O, Walker, RJ, de Mestral, C, Nathens, A, Stukel, TA et al.. Research methodologies for eliciting patients' preferences in invasive procedures: a scoping review. Langenbecks Arch Surg. 2024;409 (1):328. doi: 10.1007/s00423-024-03520-8. PubMed PMID:39470867 .
  2. Telesnicki, T, Nantais, J, De Mestral, C, de Buck van Overstraeten, A, Gomez, D. Long-term Outcomes Following Non-operative Management of Acute Appendicitis: A Population-based Analysis. Ann Surg. 2024; :. doi: 10.1097/SLA.0000000000006555. PubMed PMID:39411865 .
  3. Li, B, Beaton, D, Lee, DS, Aljabri, B, Al-Omran, L, Wijeysundera, DN et al.. Comprehensive review of virtual assistants in vascular surgery. Semin Vasc Surg. 2024;37 (3):342-349. doi: 10.1053/j.semvascsurg.2024.07.001. PubMed PMID:39277351 .
  4. de Mestral, C. Can Rivaroxaban Improve Claudication Symptoms? A Promise Never Made. NEJM Evid. 2024;3 (9):EVIDe2400262. doi: 10.1056/EVIDe2400262. PubMed PMID:39189864 .
  5. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Al-Omran, L, Wijeysundera, DN et al.. Using Machine Learning to Predict Outcomes Following Transfemoral Carotid Artery Stenting. J Am Heart Assoc. 2024;13 (17):e035425. doi: 10.1161/JAHA.124.035425. PubMed PMID:39189482 .
  6. Sankar, A, Stukel, TA, Baxter, NN, Wijeysundera, DN, Hwang, SW, Wilton, AS et al.. Disparities in surgery rates during the COVID-19 pandemic: retrospective study. BJS Open. 2024;8 (4):. doi: 10.1093/bjsopen/zrae088. PubMed PMID:39186678 PubMed Central PMC11346633.
  7. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Al-Omran, L, Wijeysundera, DN et al.. Predicting inferior vena cava filter complications using machine learning. J Vasc Surg Venous Lymphat Disord. 2024;12 (6):101943. doi: 10.1016/j.jvsv.2024.101943. PubMed PMID:39084408 PubMed Central PMC11523346.
  8. Guilcher, SJT, Mayo, AL, Swayze, S, de Mestral, C, Viana, R, Payne, MW et al.. Patterns of inpatient acute care and emergency department utilization within one year post-initial amputation among individuals with dysvascular major lower extremity amputation in Ontario, Canada: A population-based retrospective cohort study. PLoS One. 2024;19 (7):e0305381. doi: 10.1371/journal.pone.0305381. PubMed PMID:38990832 PubMed Central PMC11238985.
  9. Telesnicki, TT, Simpson, AN, de Mestral, C, Baxter, NN, Urbach, DR, Gomez, D et al.. Recommendations for Recovery of the COVID-19 Pandemic-related Diagnostic, Screening, and Procedure Backlog in Ontario: A Survey of Healthcare Leaders. Clin Invest Med. 2024;47 (2):4-11. doi: 10.3138/cim-2024-2655. PubMed PMID:38958478 .
  10. Walker, RJB, Stukel, TA, de Mestral, C, Nathens, A, Breau, RH, Hanna, WC et al.. Hospital volume-outcome relationships for robot-assisted surgeries: a population-based analysis. Surg Endosc. 2024;38 (8):4531-4542. doi: 10.1007/s00464-024-10998-2. PubMed PMID:38937312 .
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Affiliations & Other Activities

  • Surgeon, Division of Vascular Surgery, St. Michael’s Hospital
  • Assistant Professor, Department of Surgery, University of Toronto
  • Adjunct Scientist, Institute for Clinical Evaluative Sciences