Charles de Mestral




Dr. Charles de Mestral is a vascular surgeon at St. Michael’s Hospital and a Surgeon-Scientist in the Department of Surgery of the University of Toronto. He conducts research on clinical effectiveness, as well as the provision, quality and costs of surgical care.  His primary research focus is amputation prevention in people with diabetes and peripheral artery disease. His work is based out of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and ICES.

Please note: Dr. de Mestral is no longer accepting summer students.


Recent Publications

  1. Li, B, de Mestral, C, Mamdani, M, Al-Omran, M. Perceptions of Canadian vascular surgeons toward artificial intelligence and machine learning. J Vasc Surg Cases Innov Tech. 2022;8 (3):466-472. doi: 10.1016/j.jvscit.2022.06.018. PubMed PMID:36016703 PubMed Central PMC9396444.
  2. Nantais, J, Mansour, M, de Mestral, C, Jayaraman, S, Gomez, D. Administrative codes may have limited utility in diagnosing biliary colic in emergency department visits: A validation study. Ann Hepatobiliary Pancreat Surg. 2022;26 (3):277-280. doi: 10.14701/ahbps.21-171. PubMed PMID:35851329 PubMed Central PMC9428434.
  3. Patel, J, Zamzam, A, Syed, M, Blanchette, V, Cross, K, Albalawi, Z et al.. A Scoping Review of Foot Screening in Adults With Diabetes Mellitus Across Canada. Can J Diabetes. 2022;46 (5):435-440.e2. doi: 10.1016/j.jcjd.2022.01.004. PubMed PMID:35644783 .
  4. Muaddi, H, Stukel, TA, de Mestral, C, Nathens, A, Pautler, SE, Shayegan, B et al.. Adverse events following robotic surgery: population-based analysis. Br J Surg. 2022;109 (8):763-771. doi: 10.1093/bjs/znac119. PubMed PMID:35612961 .
  5. McAlister, FA, Dong, Y, Chu, A, Wang, X, Youngson, E, Quinn, KL et al.. The risk of death or unplanned readmission after discharge from a COVID-19 hospitalization in Alberta and Ontario. CMAJ. 2022;194 (19):E666-E673. doi: 10.1503/cmaj.220272. PubMed PMID:35577377 PubMed Central PMC9438727.
  6. Primary Panel:, Abramson, BL, Al-Omran, M, Anand, SS, Albalawi, Z, Coutinho, T et al.. Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease. Can J Cardiol. 2022;38 (5):560-587. doi: 10.1016/j.cjca.2022.02.029. PubMed PMID:35537813 .
  7. Syed, MH, Al-Omran, M, Ray, JG, Mamdani, M, de Mestral, C. High-Intensity Hospital Utilization Among Adults With Diabetic Foot Ulcers: A Population-based Study. Can J Diabetes. 2022;46 (4):330-336.e7. doi: 10.1016/j.jcjd.2021.10.005. PubMed PMID:35527204 .
  8. Johnson, G, Vergis, A, Unger, B, Park, J, Gillman, L, Hickey, K et al.. 2021 Canadian Surgery Forum: Virtual, online Sept. 21-24, 2021. Can J Surg. ;64 (6 Suppl 2):S80-S159. doi: 10.1503/cjs.021321. PubMed PMID:35483046 PubMed Central PMC8677574.
  9. Gomez, D, Nantais, J, Telesnicki, T, de Mestral, C, Wilton, AS, Stukel, TA et al.. A Population-based Analysis of the COVID-19 Generated Surgical Backlog and Associated Emergency Department Presentations for Inguinal Hernias and Gallstone Disease. Ann Surg. 2022;275 (5):836-841. doi: 10.1097/SLA.0000000000005403. PubMed PMID:35081578 PubMed Central PMC9083314.
  10. Muaddi, H, Zhao, X, Leonardelli, GJ, de Mestral, C, Nathens, A, Stukel, TA et al.. Fear of innovation: public's perception of robotic surgery. Surg Endosc. 2022;36 (8):6076-6083. doi: 10.1007/s00464-022-09011-5. PubMed PMID:35059838 .
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Affiliations & Other Activities

  • Surgeon, Division of Vascular Surgery, St. Michael’s Hospital
  • Assistant Professor, Department of Surgery, University of Toronto
  • Adjunct Scientist, Institute for Clinical Evaluative Sciences