Corinne E. Fischer



Research Programs


Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Riek, HC, Brien, DC, Coe, BC, Huang, J, Perkins, JE, Yep, R et al.. Cognitive correlates of antisaccade behaviour across multiple neurodegenerative diseases. Brain Commun. 2023;5 (2):fcad049. doi: 10.1093/braincomms/fcad049. PubMed PMID:36970045 PubMed Central PMC10036290.
  2. Golas, AC, Salwierz, P, Rajji, TK, Bowie, CR, Butters, MA, Fischer, CE et al.. Assessing the Role of Past Depression in Patients with Mild Cognitive Impairment, with and without Biomarkers for Alzheimer's Disease. J Alzheimers Dis. 2023; :. doi: 10.3233/JAD-221097. PubMed PMID:36911939 .
  3. Ahangari, N, Fischer, CE, Schweizer, TA, Munoz, DG. Cognitive resilience and severe Alzheimer's disease neuropathology. Aging Brain. 2023;3 :100065. doi: 10.1016/j.nbas.2023.100065. PubMed PMID:36911256 PubMed Central PMC9997171.
  4. Sano, M, Cummings, J, Auer, S, Bergh, S, Fischer, CE, Gerritsen, D et al.. Agitation in cognitive disorders: Progress in the International Psychogeriatric Association consensus clinical and research definition. Int Psychogeriatr. 2023; :1-13. doi: 10.1017/S1041610222001041. PubMed PMID:36880250 .
  5. Cummings, J, Sano, M, Auer, S, Bergh, S, Fischer, CE, Gerritsen, D et al.. Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm. Int Psychogeriatr. 2023; :1-12. doi: 10.1017/S104161022200103X. PubMed PMID:36876335 .
  6. Valcic, M, Khoury, MA, Kim, J, Fornazzari, L, Churchill, NW, Ismail, Z et al.. Correction: Valcic et al. Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort. Brain Sci. 2022, 12, 1266. Brain Sci. 2022;13 (1):. doi: 10.3390/brainsci13010064. PubMed PMID:36672138 PubMed Central PMC9831142.
  7. Kapustin, D, Zarei, S, Wang, W, Binns, MA, McLaughlin, PM, Abrahao, A et al.. Neuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function. Can J Psychiatry. 2023; :7067437221147443. doi: 10.1177/07067437221147443. PubMed PMID:36637224 .
  8. Fischer, CE. Biomarkers of neurodegeneration among patients with very late-onset schizophrenia-like psychosis: future implications. Int Psychogeriatr. 2022; :1-9. doi: 10.1017/S1041610222001181. PubMed PMID:36515016 .
  9. Fischer, CE, Namasivayam, A, Crawford-Holland, L, Hakobyan, N, Schweizer, TA, Munoz, DG et al.. Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment. Psychiatr Clin North Am. 2022;45 (4):691-705. doi: 10.1016/j.psc.2022.07.001. PubMed PMID:36396273 .
  10. Dissanayake, AS, Tan, YB, Bowie, CR, Butters, MA, Flint, AJ, Gallagher, D et al.. Sex Modifies the Associations of APOEɛ4 with Neuropsychiatric Symptom Burden in Both At-Risk and Clinical Cohorts of Alzheimer's Disease. J Alzheimers Dis. 2022;90 (4):1571-1588. doi: 10.3233/JAD-220586. PubMed PMID:36314203 .
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS