Corinne E. Fischer



Research Programs


Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Azami, H, Zrenner, C, Brooks, H, Zomorrodi, R, Blumberger, DM, Fischer, CE et al.. Beta to theta power ratio in EEG periodic components as a potential biomarker in mild cognitive impairment and Alzheimer's dementia. Alzheimers Res Ther. 2023;15 (1):133. doi: 10.1186/s13195-023-01280-z. PubMed PMID:37550778 PubMed Central PMC10405483.
  2. Zebarth, J, Kamal, R, Perlman, G, Ouk, M, Xiong, LY, Yu, D et al.. Perivascular spaces mediate a relationship between diabetes and other cerebral small vessel disease markers in cerebrovascular and neurodegenerative diseases. J Stroke Cerebrovasc Dis. 2023;32 (9):107273. doi: 10.1016/j.jstrokecerebrovasdis.2023.107273. PubMed PMID:37542762 .
  3. Ozzoude, M, Varriano, B, Beaton, D, Ramirez, J, Adamo, S, Holmes, MF et al.. White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases. Alzheimers Res Ther. 2023;15 (1):114. doi: 10.1186/s13195-023-01257-y. PubMed PMID:37340319 PubMed Central PMC10280981.
  4. Dilliott, AA, Berberian, SA, Sunderland, KM, Binns, MA, Zimmer, J, Ozzoude, M et al.. Rare neurovascular genetic and imaging markers across neurodegenerative diseases. Alzheimers Dement. 2023; :. doi: 10.1002/alz.13316. PubMed PMID:37272523 .
  5. Marawi, T, Zhukovsky, P, Rashidi-Ranjbar, N, Bowie, CR, Brooks, H, Fischer, CE et al.. Brain-Cognition Associations in Older Patients With Remitted Major Depressive Disorder or Mild Cognitive Impairment: A Multivariate Analysis of Gray and White Matter Integrity. Biol Psychiatry. 2023;94 (12):913-923. doi: 10.1016/j.biopsych.2023.05.018. PubMed PMID:37271418 .
  6. Feng, V, Lanctot, K, Herrmann, N, Kiss, A, Fischer, CE, Flint, AJ et al.. Lipopolysaccharide, Immune Biomarkers and Cerebral Amyloid-Beta Deposition in Older Adults With Mild Cognitive Impairment & Major Depressive Disorder. Am J Geriatr Psychiatry. 2023;31 (10):786-795. doi: 10.1016/j.jagp.2023.04.014. PubMed PMID:37211499 .
  7. Riek, HC, Brien, DC, Coe, BC, Huang, J, Perkins, JE, Yep, R et al.. Cognitive correlates of antisaccade behaviour across multiple neurodegenerative diseases. Brain Commun. 2023;5 (2):fcad049. doi: 10.1093/braincomms/fcad049. PubMed PMID:36970045 PubMed Central PMC10036290.
  8. Golas, AC, Salwierz, P, Rajji, TK, Bowie, CR, Butters, MA, Fischer, CE et al.. Assessing the Role of Past Depression in Patients with Mild Cognitive Impairment, with and without Biomarkers for Alzheimer's Disease. J Alzheimers Dis. 2023;92 (4):1219-1227. doi: 10.3233/JAD-221097. PubMed PMID:36911939 PubMed Central PMC10200207.
  9. Ahangari, N, Fischer, CE, Schweizer, TA, Munoz, DG. Cognitive resilience and severe Alzheimer's disease neuropathology. Aging Brain. 2023;3 :100065. doi: 10.1016/j.nbas.2023.100065. PubMed PMID:36911256 PubMed Central PMC9997171.
  10. Sano, M, Cummings, J, Auer, S, Bergh, S, Fischer, CE, Gerritsen, D et al.. Agitation in cognitive disorders: Progress in the International Psychogeriatric Association consensus clinical and research definition. Int Psychogeriatr. 2023; :1-13. doi: 10.1017/S1041610222001041. PubMed PMID:36880250 PubMed Central PMC10684256.
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS