Corinne E. Fischer



Research Programs


Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Valcic, M, Khoury, MA, Kim, J, Fornazzari, L, Churchill, NW, Ismail, Z et al.. Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort. Brain Sci. 2022;12 (9):. doi: 10.3390/brainsci12091266. PubMed PMID:36139002 .
  2. Milanovic, M, Wood-Ross, C, Butters, MA, Fischer, CE, Flint, AJ, Gerretsen, P et al.. Self- versus informant-report of cognitive decline in mild cognitive impairment: Concordance with cognitive and functional performance. Neuropsychology. 2022; :. doi: 10.1037/neu0000842. PubMed PMID:35925736 .
  3. Jeremian, R, Malinowski, A, Chaudhary, Z, Srivastava, A, Qian, J, Zai, C et al.. Epigenetic age dysregulation in individuals with bipolar disorder and schizophrenia. Psychiatry Res. 2022;315 :114689. doi: 10.1016/j.psychres.2022.114689. PubMed PMID:35849977 .
  4. AgĂĽera-Ortiz, L, Babulal, GM, Bruneau, MA, Creese, B, D'Antonio, F, Fischer, CE et al.. Psychosis as a Treatment Target in Dementia: A Roadmap for Designing Interventions. J Alzheimers Dis. 2022;88 (4):1203-1228. doi: 10.3233/JAD-215483. PubMed PMID:35786651 .
  5. Dilliott, AA, Zhang, KK, Wang, J, Abrahao, A, Binns, MA, Black, SE et al.. Targeted copy number variant identification across the neurodegenerative disease spectrum. Mol Genet Genomic Med. 2022;10 (8):e1986. doi: 10.1002/mgg3.1986. PubMed PMID:35666053 PubMed Central PMC9356547.
  6. Fischer, CE. Commentary on Agitation in Cognitive Disorders: Use of the National Alzheimer's Coordinating Center Uniform Data Set (NACC-UDS) to Evaluate International Psychogeriatric Association Definition. Am J Geriatr Psychiatry. 2022; :. doi: 10.1016/j.jagp.2022.04.014. PubMed PMID:35641401 .
  7. Beaton, D, McLaughlin, PM, Orange, JB, Munoz, DP, Mandzia, J, Abrahao, A et al.. Caregiving concerns and clinical characteristics across neurodegenerative and cerebrovascular disorders in the Ontario neurodegenerative disease research initiative. Int J Geriatr Psychiatry. 2022;37 (6):. doi: 10.1002/gps.5727. PubMed PMID:35633037 .
  8. Khoury, MA, Bahsoun, MA, Fadhel, A, Shunbuli, S, Venkatesh, S, Ghazvanchahi, A et al.. Delusional Severity Is Associated with Abnormal Texture in FLAIR MRI. Brain Sci. 2022;12 (5):. doi: 10.3390/brainsci12050600. PubMed PMID:35624987 PubMed Central PMC9139341.
  9. Mirjalili, M, Zomorrodi, R, Daskalakis, ZJ, Hill, SL, Kumar, S, Blumberger, DM et al.. Cognitive control, interference inhibition, and ordering of information during working memory in younger and older healthy adults. Geroscience. 2022; :. doi: 10.1007/s11357-022-00577-5. PubMed PMID:35553346 .
  10. Rashidi-Ranjbar, N, Rajji, TK, Hawco, C, Kumar, S, Herrmann, N, Mah, L et al.. Association of functional connectivity of the executive control network or default mode network with cognitive impairment in older adults with remitted major depressive disorder or mild cognitive impairment. Neuropsychopharmacology. 2022; :. doi: 10.1038/s41386-022-01308-2. PubMed PMID:35410366 .
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS