Corinne E. Fischer



Research Programs


Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Nader, G, Qureshi, M, Chaudhary, Z, Fischer, CE, Graff-Guerrero, A, Gerretsen, P et al.. Effect of personality traits, psychological resilience and life adversities on lifetime violence trajectories: A novel classification model in schizophrenia. Psychiatry Res. 2024;339 :116044. doi: 10.1016/j.psychres.2024.116044. PubMed PMID:38972181 .
  2. Andriuta, D, Ottoy, J, Ruthirakuhan, M, Feliciano, G, Dilliott, AA, Hegele, RA et al.. Perivascular spaces, plasma GFAP, and speeded executive function in neurodegenerative diseases. Alzheimers Dement. 2024; :. doi: 10.1002/alz.14081. PubMed PMID:38961774 .
  3. Naveed, K, Rashidi-Ranjbar, N, Kumar, S, Zomorrodi, R, Blumberger, DM, Fischer, CE et al.. Effect of dorsolateral prefrontal cortex structural measures on neuroplasticity and response to paired-associative stimulation in Alzheimer's dementia. Philos Trans R Soc Lond B Biol Sci. 2024;379 (1906):20230233. doi: 10.1098/rstb.2023.0233. PubMed PMID:38853564 .
  4. Patterson, RA, Brooks, H, Mirjalili, M, Rashidi-Ranjbar, N, Zomorrodi, R, Blumberger, DM et al.. Neurophysiological and other features of working memory in older adults at risk for dementia. Cogn Neurodyn. 2024;18 (3):795-811. doi: 10.1007/s11571-023-09938-y. PubMed PMID:38826646 PubMed Central PMC11143125.
  5. Khoury, MA, Churchill, NW, Di Battista, A, Graham, SJ, Symons, S, Troyer, AK et al.. History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment. J Neurol. 2024;271 (7):4540-4550. doi: 10.1007/s00415-024-12369-2. PubMed PMID:38717612 .
  6. Guan, DX, Churchill, NW, Fischer, CE, Graham, SJ, Schweizer, TA. Neuroanatomical correlates of distracted straight driving performance: a driving simulator MRI study across the lifespan. Front Aging Neurosci. 2024;16 :1369179. doi: 10.3389/fnagi.2024.1369179. PubMed PMID:38706457 PubMed Central PMC11066182.
  7. Brooks, H, Wang, W, Zomorrodi, R, Blumberger, DM, Bowie, CR, Daskalakis, ZJ et al.. Cognitive function based on theta-gamma coupling vs. clinical diagnosis in older adults with mild cognitive impairment with or without major depressive disorder. Transl Psychiatry. 2024;14 (1):153. doi: 10.1038/s41398-024-02856-5. PubMed PMID:38503740 PubMed Central PMC10951346.
  8. Rashidi-Ranjbar, N, Churchill, NW, Black, SE, Kumar, S, Tartaglia, MC, Freedman, M et al.. Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment, cerebrovascular disease and Parkinson disease: A cross sectional and longitudinal study. Int J Geriatr Psychiatry. 2024;39 (3):e6074. doi: 10.1002/gps.6074. PubMed PMID:38491809 .
  9. Marawi, T, Zhukovsky, P, Brooks, H, Bowie, CR, Butters, MA, Fischer, CE et al.. Heterogeneity of Cognition in Older Adults with Remitted Major Depressive Disorder: A Latent Profile Analysis. Am J Geriatr Psychiatry. 2024;32 (7):867-878. doi: 10.1016/j.jagp.2024.01.225. PubMed PMID:38403532 .
  10. Anderson, JAE, Rashidi-Ranjbar, N, Nazeri, A, Chad, JA, Zhukovsky, P, Mulsant, BH et al.. Age-Related Alterations in Gray Matter Microstructure in Older People With Remitted Major Depression at Risk for Dementia. Biol Psychiatry Glob Open Sci. 2024;4 (1):374-384. doi: 10.1016/j.bpsgos.2023.08.018. PubMed PMID:38298786 PubMed Central PMC10829634.
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS