David Jenkins




Educated at Oxford University, Dr. David Jenkins is currently a Professor in both the Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, a Staff Physician in the Division of Endocrinology and Metabolism, the Director of the Clinical Nutrition and Risk Factor Modification Center, and a Scientist in the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. He has served on committees in Canada and the United States that have formulated nutritional guidelines for the treatment of diabetes and recommendations for fibre and macronutrient intake (fat protein and carbohydrates) for the general population (including the Dietary Reference intake or DRIs) under the joint United States-Canada DRI system (RDAs) of the National Academy of Sciences (Washington, DC). He led the team that first defined and explored the concept of the glycemic index of foods. He was the first to demonstrate the breadth of metabolic effects of viscous soluble fiber (as found in fruit, certain beans, oats barley) on blood glucose and cholesterol lowering of relevance to prevention and treatment of diabetes and heart disease. His studies on combining cholesterol lowering food components (dietary portfolio) have been recognized as creating an effective dietary alternative to drug therapy (statins) for lower risk people. In an important study, he compared a dietary portfolio with all food provided with a statin in the same people and demonstrated that the effects of both were comparable. The dietary portfolio, on the basis of this and other studies including a major cross Canada real world study, was the only dietary approach referenced in 2004 Guidelines update of the US National Cholesterol Education Program (ATP III) and recommended in the Canadian Cardiovascular Society (CCS) guidelines for 2012 and the European Atherosclerosis Society consensus statement (2015). He has received many National and International awards in recognition of his contribution to nutrition research. He believes in the value of plant based diets, and that a major effort is required to mount large studies to determine the extent of their health benefits. He also believes that diets have to be environmentally sustainable.

Please note: Dr. Jenkins is currently accepting volunteer students.

Recent Publications

  1. Chiavaroli, L, Cheung, A, Ayoub-Charette, S, Ahmed, A, Lee, D, Au-Yeung, F et al.. Important food sources of fructose-containing sugars and adiposity: A systematic review and meta-analysis of controlled feeding trials. Am J Clin Nutr. 2023; :. doi: 10.1016/j.ajcnut.2023.01.023. PubMed PMID:36842451 .
  2. Glenn, AJ, Aune, D, Freisling, H, Mohammadifard, N, Kendall, CWC, Salas-Salvadó, J et al.. Nuts and Cardiovascular Disease Outcomes: A Review of the Evidence and Future Directions. Nutrients. 2023;15 (4):. doi: 10.3390/nu15040911. PubMed PMID:36839269 PubMed Central PMC9964942.
  3. Nishi, SK, Viguiliouk, E, Kendall, CWC, Jenkins, DJA, Hu, FB, Sievenpiper, JL et al.. Nuts in the Prevention and Management of Type 2 Diabetes. Nutrients. 2023;15 (4):. doi: 10.3390/nu15040878. PubMed PMID:36839236 PubMed Central PMC9965730.
  4. Carey, CN, Paquette, M, Sahye-Pudaruth, S, Dadvar, A, Dinh, D, Khodabandehlou, K et al.. The Environmental Sustainability of Plant-Based Dietary Patterns: A Scoping Review. J Nutr. 2023;153 (3):857-869. doi: 10.1016/j.tjnut.2023.02.001. PubMed PMID:36809853 .
  5. Simonneau, G, Fadel, E, Vonk Noordegraaf, A, Toshner, M, Lang, IM, Klok, FA et al.. Highlights from the International Chronic Thromboembolic Pulmonary Hypertension Congress 2021. Eur Respir Rev. 2023;32 (167):. doi: 10.1183/16000617.0132-2022. PubMed PMID:36754432 PubMed Central PMC9910339.
  6. Vitale, S, Palumbo, E, Polesel, J, Hebert, JR, Shivappa, N, Montagnese, C et al.. One-year nutrition counselling in the context of a Mediterranean diet reduced the dietary inflammatory index in women with breast cancer: a role for the dietary glycemic index. Food Funct. 2023;14 (3):1560-1572. doi: 10.1039/d2fo02198f. PubMed PMID:36655860 .
  7. Jenkins, DJA, Chiavaroli, L, Mirrahimi, A, Mitchell, S, Faulkner, D, Sahye-Pudaruth, S et al.. Glycemic Index Versus Wheat Fiber on Arterial Wall Damage in Diabetes: A Randomized Controlled Trial. Diabetes Care. 2022;45 (12):2862-2870. doi: 10.2337/dc22-1028. PubMed PMID:36326712 PubMed Central PMC9862401.
  8. Mahdavi, S, Jenkins, DJA, El-Sohemy, A. Genetic variation in 9p21, dietary patterns, and insulin sensitivity. Front Genet. 2022;13 :988873. doi: 10.3389/fgene.2022.988873. PubMed PMID:36313440 PubMed Central PMC9616109.
  9. Jenkins, DJA, Kendall, CWC, Sievenpiper, JL. Carbohydrate quality and cardiovascular disease: Need for trials. Trends Cardiovasc Med. 2022; :. doi: 10.1016/j.tcm.2022.09.008. PubMed PMID:36252732 .
  10. Qi, X, Chiavaroli, L, Lee, D, Ayoub-Charette, S, Khan, TA, Au-Yeung, F et al.. Effect of Important Food Sources of Fructose-Containing Sugars on Inflammatory Biomarkers: A Systematic Review and Meta-Analysis of Controlled Feeding Trials. Nutrients. 2022;14 (19):. doi: 10.3390/nu14193986. PubMed PMID:36235639 PubMed Central PMC9572084.
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Affiliations & Other Activities

  • Director, Clinical Nutrition and Risk Factor Modification Centre, St. Michael’s Hospital
  • Staff Physician, Division of Endocrinology, Department of Medicine, St. Michael’s Hospital
  • Professor and Canada Research Chair in Nutrition and Metabolism, Dept. of Medicine and Nutritional Sciences, Faculty of Medicine, University of Toronto
  • Canada Research Chair in Nutrition and Metabolism