David Munoz



Research Programs


Dr. David Munoz holds an MD from Navarre and MSc in Pathology from Queen’s University, Ontario. He trained in neurology and neuropathology and became a Fellow of the Royal College of Physicians and Surgeons of Canada in 1984. He has practiced in Vermont, Saskatoon, London (ON), Madrid, and Toronto, and briefly in Vancouver. He is currently a Neuropathologist and Head, Division of Pathology at St. Michael’s Hospital, Toronto, and Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto. He is the author of 194 peer-reviewed papers, 20 book chapters, and co-author of one book. He has held research grants in Canada (Medical Research Council and Canadian Institutes of Health Research) and USA (National Institutes of Health).

His research interest is focused on neuropathology, particularly the mechanisms of development and progression of degenerative diseases of the brain, including Alzheimer’s disease, the non-Alzheimer dementias, movement disorders, and amyotrophic lateral sclerosis. His other research interest in neurooncology is derived from his clinical practice.

Please note: Dr. D. Munoz is not taking any summer students

Recent Publications

  1. Alfalahi, A, Omar, AI, Fox, K, Spears, J, Sharma, M, Bharatha, A et al.. Epstein-Barr Virus-Associated Smooth-Muscle Tumor of the Brain. AJNR Am J Neuroradiol. 2024; :. doi: 10.3174/ajnr.A8258. PubMed PMID:38724198 .
  2. Khoury, MA, Churchill, NW, Di Battista, A, Graham, SJ, Symons, S, Troyer, AK et al.. History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment. J Neurol. 2024; :. doi: 10.1007/s00415-024-12369-2. PubMed PMID:38717612 .
  3. Malik, P, Chen, YA, Mathew, BB, Munoz, DG, Selvi, BT, Vanjare, HA et al.. Topographical distribution and prevalence of basal duct-like recess sign in a cohort of Papillary Craniopharyngioma-novel findings and implications. Neuroradiology. 2024;66 (6):947-953. doi: 10.1007/s00234-024-03355-6. PubMed PMID:38625616 .
  4. Millward, CP, Keshwara, SM, Armstrong, TS, Barrington, H, Bell, S, Brodbelt, AR et al.. The outcomes measured and reported in intracranial meningioma clinical trials: A systematic review. Neurooncol Adv. 2024;6 (1):vdae030. doi: 10.1093/noajnl/vdae030. PubMed PMID:38596717 PubMed Central PMC11003530.
  5. Millward, CP, Islim, AI, Armstrong, TS, Barrington, H, Bell, S, Brodbelt, AR et al.. The outcomes measured and reported in observational studies of incidental and untreated intracranial meningioma: A systematic review. Neurooncol Adv. 2024;6 (1):vdae042. doi: 10.1093/noajnl/vdae042. PubMed PMID:38596715 PubMed Central PMC11003528.
  6. Coe, BC, Huang, J, Brien, DC, White, BJ, Yep, R, Munoz, DP et al.. Automated Analysis Pipeline for Extracting Saccade, Pupil, and Blink Parameters Using Video-Based Eye Tracking. Vision (Basel). 2024;8 (1):. doi: 10.3390/vision8010014. PubMed PMID:38535763 PubMed Central PMC10975925.
  7. Kertesz, A, Finger, E, Munoz, DG. Progress in Primary Progressive Aphasia: A Review. Cogn Behav Neurol. 2024;37 (1):3-12. doi: 10.1097/WNN.0000000000000365. PubMed PMID:38498721 .
  8. Rashidi-Ranjbar, N, Churchill, NW, Black, SE, Kumar, S, Tartaglia, MC, Freedman, M et al.. Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment, cerebrovascular disease and Parkinson disease: A cross sectional and longitudinal study. Int J Geriatr Psychiatry. 2024;39 (3):e6074. doi: 10.1002/gps.6074. PubMed PMID:38491809 .
  9. Malik, P, Soliman, R, Chen, YA, Munoz, DG, Das, S, Bharatha, A et al.. Patterns of T2-FLAIR discordance across a cohort of adult-type diffuse gliomas and deviations from the classic T2-FLAIR mismatch sign. Neuroradiology. 2024;66 (4):521-530. doi: 10.1007/s00234-024-03297-z. PubMed PMID:38347151 .
  10. van der Meulen, M, Ramos, RC, Voisin, MR, Patil, V, Wei, Q, Singh, O et al.. Differences in methylation profiles between long-term survivors and short-term survivors of IDH-wild-type glioblastoma. Neurooncol Adv. 2024;6 (1):vdae001. doi: 10.1093/noajnl/vdae001. PubMed PMID:38312227 PubMed Central PMC10838123.
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Affiliations & Other Activities

  • Head, Division of Pathology, St. Michael’s Hospital
  • Professor, Laboratory Medicine and Pathobiology, University of Toronto