David Munoz



Research Programs


Dr. David Munoz holds an MD from Navarre and MSc in Pathology from Queen’s University, Ontario. He trained in neurology and neuropathology and became a Fellow of the Royal College of Physicians and Surgeons of Canada in 1984. He has practiced in Vermont, Saskatoon, London (ON), Madrid, and Toronto, and briefly in Vancouver. He is currently a Neuropathologist and Head, Division of Pathology at St. Michael’s Hospital, Toronto, and Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto. He is the author of 194 peer-reviewed papers, 20 book chapters, and co-author of one book. He has held research grants in Canada (Medical Research Council and Canadian Institutes of Health Research) and USA (National Institutes of Health).

His research interest is focused on neuropathology, particularly the mechanisms of development and progression of degenerative diseases of the brain, including Alzheimer’s disease, the non-Alzheimer dementias, movement disorders, and amyotrophic lateral sclerosis. His other research interest in neurooncology is derived from his clinical practice.

Please note: Dr. D. Munoz is not taking any summer students

Recent Publications

  1. Huang, J, Brien, D, Coe, BC, Longoni, G, Mabbott, DJ, Munoz, DP et al.. Delayed oculomotor response associates with optic neuritis in youth with demyelinating disorders. Mult Scler Relat Disord. 2023;79 :104969. doi: 10.1016/j.msard.2023.104969. PubMed PMID:37660456 .
  2. Wang, JZ, Nassiri, F, Landry, AP, Patil, V, Rebchuk, A, Merali, ZA et al.. Fractionated radiotherapy for surgically resected intracranial meningiomas: A multicentre retrospective cohort study. Radiother Oncol. 2023;188 :109861. doi: 10.1016/j.radonc.2023.109861. PubMed PMID:37619659 .
  3. Ozzoude, M, Varriano, B, Beaton, D, Ramirez, J, Adamo, S, Holmes, MF et al.. White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases. Alzheimers Res Ther. 2023;15 (1):114. doi: 10.1186/s13195-023-01257-y. PubMed PMID:37340319 PubMed Central PMC10280981.
  4. Vaccarino, AL, Black, SE, Gilbert Evans, S, Frey, BN, Javadi, M, Kennedy, SH et al.. Rasch analyses of the Quick Inventory of Depressive Symptomatology Self-Report in neurodegenerative and major depressive disorders. Front Psychiatry. 2023;14 :1154519. doi: 10.3389/fpsyt.2023.1154519. PubMed PMID:37333922 PubMed Central PMC10273843.
  5. Wang, JZ, Landry, AP, Nassiri, F, Merali, ZA, Patel, Z, Lee, G et al.. Outcomes and predictors of response to fractionated radiotherapy as primary treatment for intracranial meningiomas. Clin Transl Radiat Oncol. 2023;41 :100631. doi: 10.1016/j.ctro.2023.100631. PubMed PMID:37168253 PubMed Central PMC10165177.
  6. Riek, HC, Brien, DC, Coe, BC, Huang, J, Perkins, JE, Yep, R et al.. Cognitive correlates of antisaccade behaviour across multiple neurodegenerative diseases. Brain Commun. 2023;5 (2):fcad049. doi: 10.1093/braincomms/fcad049. PubMed PMID:36970045 PubMed Central PMC10036290.
  7. Ahangari, N, Fischer, CE, Schweizer, TA, Munoz, DG. Cognitive resilience and severe Alzheimer's disease neuropathology. Aging Brain. 2023;3 :100065. doi: 10.1016/j.nbas.2023.100065. PubMed PMID:36911256 PubMed Central PMC9997171.
  8. Brien, DC, Riek, HC, Yep, R, Huang, J, Coe, B, Areshenkoff, C et al.. Classification and staging of Parkinson's disease using video-based eye tracking. Parkinsonism Relat Disord. 2023;110 :105316. doi: 10.1016/j.parkreldis.2023.105316. PubMed PMID:36822878 .
  9. Valcic, M, Khoury, MA, Kim, J, Fornazzari, L, Churchill, NW, Ismail, Z et al.. Correction: Valcic et al. Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort. Brain Sci. 2022, 12, 1266. Brain Sci. 2022;13 (1):. doi: 10.3390/brainsci13010064. PubMed PMID:36672138 PubMed Central PMC9831142.
  10. Attia, EM, Sharma, S, Woodley-Cook, J, Spears, J, Munoz, DG. Cervical Intramedullary Solitary Fibrous Tumor. Can J Neurol Sci. 2023; :1-3. doi: 10.1017/cjn.2023.2. PubMed PMID:36660933 .
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Affiliations & Other Activities

  • Head, Division of Pathology, St. Michael’s Hospital
  • Professor, Laboratory Medicine and Pathobiology, University of Toronto