Research Interests
Mesenchymal stem/stromal cell therapy for sepsis and Acute Respiratory Distress Syndrome, macrophage biology, ex-vivo lung perfusion, carbon dioxide and critical illness, systematic review/meta-analysis of interventions in anesthesia and intensive care
1. Curley GF, Ansari B, Hayes M, Devaney J, O’Toole D, O’Brien T, Laffey JG. Effects of intra-tracheal Mesenchymal Stem Cells therapy during recovery and resolution following Ventilator Induced Lung Injury. Anesthesiology 2013 Apr;118(4):924-932
2. Curley GF, Hayes M, Ansari B, Shaw G, Ryan A, Barry F, O’Brien T, O’Toole D, Laffey JG. Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat. Thorax. 2012 Jun;67(6):496-501
3. Curley G, Contreras M, O’Toole B, Higgins B, O’Kane C, McAuley D, Laffey JG. Evolution of the inflammatory and fibroproliferative responses during resolution and repair following Ventilator Induced Lung Injury. Anesthesiology 2011 Nov;115(5):1022-32
4. Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: More harm than benefit. Crit Care Med. 2010 May;38(5):1348-59.2010 Mar 11
5. Curley GF, Laffey JG, Kavanagh BP. Point-Counterpoint Series: There IS added benefit to providing permissive hypercapnia in the treatment of ARDS. Journal of Physiology, Jun 1;591(Pt 11):2763-5