Biography

Dr. Haibo Zhang is a Staff Scientist in the Keenan Research Centre for Biomedical Science of St. Michael’s Hospital. He is a Professor of Anesthesia, Medicine and Physiology at the University of Toronto. His translational research program focuses on the mechanisms and therapy of acute lung injury and sepsis. He has published over 250 peer-reviewed articles, and is the recipient of enormous research grants and a number of research awards, including Premier’s Research Excellence Award (Ontario), a New Investigator Award from the Canadian Institutes of Health Research (CIHR), and Fellow of Canadian Academy of Health Science. He serves on a number of academic and appointment committees at the Institute of Medical Sciences (IMS), University of Toronto and at St. Michael’s Hospital. He has trained over 90 MSc and PhD students, and post-doctoral fellows.

He has served on the Standing Committee of Critical Care Assembly, the American Thoracic Society in 2005-2006, Associate Editor, Intensive Care Medicine in 2007-2013, and Editorial Boards on a number of medical journals. He was a member of grant and award committees of CIHR since 2012 and is a member of College of Reviewer since 2016, a guest grant reviewer for European nations (Austria, Belgium, Germany, Holland, Israel, UK and Italy) since 2010. He is Theme Lead of Biomaterial, Tissue Injury and Repair at the Institute of Biomedical Engineering, Science and Technology (iBEST), a partnership between Ryerson University and St. Michael’s Hospital since 2017.

Recent Publications

  1. Zhu, J, Li, Y, Liang, J, Mubareka, S, Slutsky, AS, Zhang, H et al.. The Potential Protective Role of GS-441524, a Metabolite of the Prodrug Remdesivir, in Vaccine Breakthrough SARS-CoV-2 Infections. Intensive Care Res. 2022; :1-12. doi: 10.1007/s44231-022-00021-4. PubMed PMID:36407474 PubMed Central PMC9645326.
  2. Jiang, Y, Rubin, L, Zhou, Z, Zhang, H, Su, Q, Hou, ST et al.. Pharmacological therapies and drug development targeting SARS-CoV-2 infection. Cytokine Growth Factor Rev. 2022;68 :13-24. doi: 10.1016/j.cytogfr.2022.10.003. PubMed PMID:36266222 PubMed Central PMC9558743.
  3. Zhang, HB, Ding, XB, Jin, J, Guo, WP, Yang, QL, Chen, PC et al.. Predicted mouse interactome and network-based interpretation of differentially expressed genes. PLoS One. 2022;17 (4):e0264174. doi: 10.1371/journal.pone.0264174. PubMed PMID:35390003 PubMed Central PMC8989236.
  4. Liang, H, Ding, X, Yu, Y, Zhang, H, Wang, L, Kan, Q et al.. Corrigendum to "Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1" [Exp. Cell Res. (2019) 383(1) 111465 doi: 10.1016/j.yexcr.2019.06.010]. Exp Cell Res. 2022;413 (1):113048. doi: 10.1016/j.yexcr.2022.113048. PubMed PMID:35134682 .
  5. Burns, KEA, Stevenson, J, Laird, M, Adhikari, NKJ, Li, Y, Lu, C et al.. Non-invasive ventilation versus invasive weaning in critically ill adults: a systematic review and meta-analysis. Thorax. 2022;77 (8):752-761. doi: 10.1136/thoraxjnl-2021-216993. PubMed PMID:34716282 .
  6. Zhang, X, Qi, S, Duan, X, Han, B, Zhang, S, Liu, S et al.. Clinical outcomes and safety of polymyxin B in the treatment of carbapenem-resistant Gram-negative bacterial infections: a real-world multicenter study. J Transl Med. 2021;19 (1):431. doi: 10.1186/s12967-021-03111-x. PubMed PMID:34656132 PubMed Central PMC8520283.
  7. Khateeb, J, Li, Y, Zhang, H. Emerging SARS-CoV-2 variants of concern and potential intervention approaches. Crit Care. 2021;25 (1):244. doi: 10.1186/s13054-021-03662-x. PubMed PMID:34253247 PubMed Central PMC8274962.
  8. Fuller, S, Kumar, SR, Roy, N, Mahle, WT, Romano, JC, Nelson, JS et al.. The American Association for Thoracic Surgery Congenital Cardiac Surgery Working Group 2021 consensus document on a comprehensive perioperative approach to enhanced recovery after pediatric cardiac surgery. J Thorac Cardiovasc Surg. 2021;162 (3):931-954. doi: 10.1016/j.jtcvs.2021.04.072. PubMed PMID:34059337 .
  9. Gabarin, RS, Li, M, Zimmel, PA, Marshall, JC, Li, Y, Zhang, H et al.. Intracellular and Extracellular Lipopolysaccharide Signaling in Sepsis: Avenues for Novel Therapeutic Strategies. J Innate Immun. 2021;13 (6):323-332. doi: 10.1159/000515740. PubMed PMID:34004605 PubMed Central PMC8613564.
  10. Zhang, X, Cui, Y, Ding, X, Liu, S, Han, B, Duan, X et al.. Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis. Bioengineered. 2021;12 (1):1457-1470. doi: 10.1080/21655979.2021.1908029. PubMed PMID:33949285 PubMed Central PMC8806204.
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Affiliations & Other Activities

  • Professor, Department of Anesthesia, University of Toronto
  • Professor, Department of Medicine, University of Toronto
  • Professor, Department of Physiology, University of Toronto
  • Faculty Member, Institute of Medical Sciences, School of Graduate Studies, University of Toronto