Howard Ginsberg




Dr. Howard Ginsberg is a graduate from the University of Toronto Neurosurgery Program. He is trained in cranial surgery as well as both neurosurgical and orthopedic spinal surgery techniques. He completed a fellowship in spinal surgery as well as a degree in Engineering Science from the University of Toronto, and a PhD in Biomedical Engineering. He is the Spine Program Director at St. Michael’s Hospital and an Assistant Professor in the Department of Surgery.  Dr. Ginsberg’s research focuses on engineering applications to neurosurgical procedures with the goal of improving safety and outcome for patients. His current research focus is on the development of a rapid tumour diagnostic system that uses mass spectrometry guided laser ablation for molecular analysis to provide a highly precise cancer diagnosis in 10 seconds.

Please note: Dr. Ginsberg is not taking any summer students.

Recent Publications

  1. Yoshikawa, S, Nishimura, Y, Nagashima, Y, Ito, H, Oyama, T, Nishii, T et al.. Evaluation of Posterior Ligamentous Complex Injury in Thoracolumbar Burst Fractures: Correlation Analysis of CT and MRI Findings. Neurol Med Chir (Tokyo). 2023;63 (4):158-164. doi: 10.2176/jns-nmc.2021-0390. PubMed PMID:36858635 PubMed Central PMC10166606.
  2. Katz, L, Woolman, M, Kiyota, T, Pires, L, Zaidi, M, Hofer, SOP et al.. Picosecond Infrared Laser Mass Spectrometry Identifies a Metabolite Array for 10 s Diagnosis of Select Skin Cancer Types: A Proof-of-Concept Feasibility Study. Anal Chem. 2022;94 (48):16821-16830. doi: 10.1021/acs.analchem.2c03918. PubMed PMID:36395434 .
  3. Shiraishi, D, Nishimura, Y, Aguirre-Carreno, I, Hara, M, Yoshikawa, S, Eguchi, K et al.. Clinical and Radiological Clues of Traumatic Craniocervical Junction Injuries Requiring Occipitocervical Fusion to Early Diagnosis. Neurospine. 2021;18 (4):741-748. doi: 10.14245/ns.2142860.430. PubMed PMID:35000327 PubMed Central PMC8752707.
  4. Voglis, S, Romagna, A, Germans, MR, Carreno, I, Stienen, MN, Henzi, A et al.. Spinal arachnoid web-a distinct entity of focal arachnopathy with favorable long-term outcome after surgical resection: analysis of a multicenter patient population. Spine J. 2022;22 (1):126-135. doi: 10.1016/j.spinee.2021.06.018. PubMed PMID:34175468 .
  5. Woolman, M, Qiu, J, Kuzan-Fischer, CM, Ferry, I, Dara, D, Katz, L et al.. In situ tissue pathology from spatially encoded mass spectrometry classifiers visualized in real time through augmented reality. Chem Sci. 2020;11 (33):8723-8735. doi: 10.1039/d0sc02241a. PubMed PMID:34123126 PubMed Central PMC8163395.
  6. Woolman, M, Katz, L, Gopinath, G, Kiyota, T, Kuzan-Fischer, CM, Ferry, I et al.. Mass Spectrometry Imaging Reveals a Gradient of Cancer-like Metabolic States in the Vicinity of Cancer Not Seen in Morphometric Margins from Microscopy. Anal Chem. 2021;93 (10):4408-4416. doi: 10.1021/acs.analchem.0c04129. PubMed PMID:33651938 .
  7. Nishimura, Y, Hara, M, Natsume, A, Wakabayashi, T, Ginsberg, HJ. Complete resection and untethering of the cervical and thoracic spinal dermal sinus tracts in adult patients. Nagoya J Med Sci. 2020;82 (3):567-577. doi: 10.18999/nagjms.82.3.567. PubMed PMID:33132440 PubMed Central PMC7548243.
  8. Nishimura, Y, Hara, M, Awaya, T, Ando, R, Eguchi, K, Nagashima, Y et al.. Possible Double Crush Syndrome Caused by Iatrogenic Acquired Lumbosacral Epidermoid Tumor and Concomitant Sacral Tarlov Cyst. NMC Case Rep J. 2020;7 (4):195-199. doi: 10.2176/ PubMed PMID:33062568 PubMed Central PMC7538451.
  9. Afshar, ME, Abraha, HY, Bakooshli, MA, Davoudi, S, Thavandiran, N, Tung, K et al.. A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength. Sci Rep. 2020;10 (1):6918. doi: 10.1038/s41598-020-62837-8. PubMed PMID:32332853 PubMed Central PMC7181829.
  10. Wilson, JR, Cronin, S, Fehlings, MG, Kwon, BK, Badhiwala, JH, Ginsberg, HJ et al.. Epidemiology and Impact of Spinal Cord Injury in the Elderly: Results of a Fifteen-Year Population-Based Cohort Study. J Neurotrauma. 2020;37 (15):1740-1751. doi: 10.1089/neu.2020.6985. PubMed PMID:32292120 .
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Affiliations & Other Activities

  • Assistant Professor, Department of Surgery, University of Toronto
  • Assistant Professor, Department of Surgery, Institute of Biomaterials and Biomedical Engineering, University of Toronto