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Jefferson Wilson

MD, PhD, FRCSC

Scientist

Email: Jefferson.Wilson@unityhealth.to
Tel: 416-864-5920

Biography

Dr. Jefferson Wilson is a surgeon-scientist at St. Michael’s Hospital and Associate Professor in the Department of Surgery at the University of Toronto. He currently holds the Labatt Endowed Chair in Neurosurgery at Unity Health. Dr Wilson’s clinical practice is focused on the surgical management of complex disorders of the spine and spinal cord. He also leads a clinical research program investigating both traumatic and non-traumatic spinal cord injury, with a specific interest in the development of predictive models and algorithms to help guide treatment and forecast outcomes. His research has been supported through several grants from organizations including the Canadian Institutes of Health Research, the Christopher and Dana Reeve Foundation, AOSpine, Neurosurgery Research and Education Foundation and the Cervical Spine Research Society. Dr. Wilson currently chairs a national evidence based spine surgery course for residents and fellows and serves on the editorial boards of Journal of Neurosurgery Spine and Clinical Spine Surgery.

Recent Publications

  1. Davies, B, Brannigan, J, Mowforth, OD, Khan, D, McNair, AGK, Tetreault, L et al.. Secondary analysis of a James Lind Alliance priority setting partnership to facilitate knowledge translation in degenerative cervical myelopathy (DCM): insights from AO Spine RECODE-DCM. BMJ Open. 2023;13 (7):e064296. doi: 10.1136/bmjopen-2022-064296. PubMed PMID:37463815 PubMed Central PMC10357680.
  2. Balas, M, Jaja, BNR, Harrington, EM, Jack, AS, Hofereiter, J, Malhotra, AK et al.. Earlier Tracheostomy Reduces Complications in Complete Cervical Spinal Cord Injury in Real-World Practice: Analysis of a Multicenter Cohort of 2001 Patients. Neurosurgery. 2023; :. doi: 10.1227/neu.0000000000002575. PubMed PMID:37341486 .
  3. Malhotra, AK, Shakil, H, Harrington, EM, Fehlings, MG, Wilson, JR, Witiw, CD et al.. Early surgery compared to nonoperative management for mild degenerative cervical myelopathy: a cost-utility analysis. Spine J. 2023; :. doi: 10.1016/j.spinee.2023.06.003. PubMed PMID:37302415 .
  4. Fehlings, MG, Moghaddamjou, A, Harrop, JS, Stanford, R, Ball, J, Aarabi, B et al.. Safety and Efficacy of Riluzole in Acute Spinal Cord Injury Study (RISCIS): A Multi-Center, Randomized, Placebo-Controlled, Double-Blinded Trial. J Neurotrauma. 2023;40 (17-18):1878-1888. doi: 10.1089/neu.2023.0163. PubMed PMID:37279301 PubMed Central PMC10460693.
  5. Shakil, H, Jaja, BNR, Zhang, PF, Jaffe, RH, Malhotra, AK, Harrington, EM et al.. Assessment of the incremental prognostic value from the modified frailty index-5 in complete traumatic cervical spinal cord injury. Sci Rep. 2023;13 (1):7578. doi: 10.1038/s41598-023-34708-5. PubMed PMID:37165004 PubMed Central PMC10172291.
  6. Mowforth, OD, Burn, L, Khan, DZ, Yang, X, Stacpoole, SRL, Gronlund, T et al.. Lived experience-centred word clouds may improve research uncertainty gathering in priority setting partnerships. BMC Med Res Methodol. 2023;23 (1):100. doi: 10.1186/s12874-023-01897-6. PubMed PMID:37087419 PubMed Central PMC10122197.
  7. Merali, Z, Zhang, PF, Jaffe, RH, Jaja, BNR, Harrington, EM, Malhotra, AK et al.. Multicenter retrospective cohort study of the association between surgery for odontoid fractures in the elderly and in-hospital outcomes. Sci Rep. 2023;13 (1):6276. doi: 10.1038/s41598-023-33158-3. PubMed PMID:37072405 PubMed Central PMC10113203.
  8. Algarni, N, Dea, N, Evaniew, N, McIntosh, G, Jacobs, BW, Paquet, J et al.. Does Ending a Posterior Construct Proximally at C2 Versus C3 Impact Patient Reported Outcomes in Degenerative Cervical Myelopathy Patients up to 24 months After the Surgery?. Global Spine J. 2023; :21925682231166605. doi: 10.1177/21925682231166605. PubMed PMID:36960878 .
  9. Jaja, BNR, Witiw, CD, Harrington, EM, He, Y, Moghaddamjou, A, Fehlings, MG et al.. Analysis of recovery trajectories in degenerative cervical myelopathy to facilitate improved patient counseling and individualized treatment recommendations. J Neurosurg Spine. 2023; :1-9. doi: 10.3171/2023.1.SPINE221053. PubMed PMID:36933253 .
  10. Evaniew, N, Burger, LD, Dea, N, Cadotte, DW, Bailey, CS, Christie, SD et al.. Deterioration After Surgery for Degenerative Cervical Myelopathy: An Observational Study From the Canadian Spine Outcomes and Research Network. Spine (Phila Pa 1976). 2023;48 (5):310-320. doi: 10.1097/BRS.0000000000004552. PubMed PMID:36730060 .
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Affiliations & Other Activities

  • Staff Surgeon, Division of Neurosurgery, St. Michael’s Hospital
  • Assistant Professor, Department of Surgery, University of Toronto