Research Programs

Biography

Dr. Watt completed medical school at the University of Ottawa, residency in internal medicine at Western University, fellowship training in geriatric medicine at the University of Toronto, and a PhD in clinical epidemiology and health care research at the University of Toronto. She was a 2019 recipient of the CIHR Institute of Health Sciences and Policy Research Rising Star Award and the Thomas & Edna Naylor Memorial Award for the best paper based on a thesis in Health Services and Health Care Research at the Institute of Health Policy, Management and Evaluation. More recently, she was awarded the 2021 Outstanding Junior Research Manuscript by the American Geriatrics Society.

Her research focuses on using knowledge synthesis methods (e.g., pairwise and network meta-analysis) and health administrative data to better understand the comparative efficacy and safety of pharmacologic and nonpharmacologic interventions in older adults, specifically, those with geriatric syndromes such as frailty, falls and cognitive impairment. She is also supporting evidence-informed and equitable access to virtual care for older adults.

Recent Publications

  1. Li, X, Quick, C, Zhou, H, Gaynor, SM, Liu, Y, Chen, H et al.. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nat Genet. 2023;55 (1):154-164. doi: 10.1038/s41588-022-01225-6. PubMed PMID:36564505 .
  2. Li, Z, Li, X, Zhou, H, Gaynor, SM, Selvaraj, MS, Arapoglou, T et al.. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nat Methods. 2022;19 (12):1599-1611. doi: 10.1038/s41592-022-01640-x. PubMed PMID:36303018 .
  3. Jones, A, Goodarzi, Z, Lee, J, Norman, R, Wong, E, Dasgupta, M et al.. Chemical and physical restraint use during acute care hospitalization of older adults: A retrospective cohort study and time series analysis. PLoS One. 2022;17 (10):e0276504. doi: 10.1371/journal.pone.0276504. PubMed PMID:36288382 PubMed Central PMC9604990.
  4. Selvaraj, MS, Li, X, Li, Z, Pampana, A, Zhang, DY, Park, J et al.. Whole genome sequence analysis of blood lipid levels in >66,000 individuals. Nat Commun. 2022;13 (1):5995. doi: 10.1038/s41467-022-33510-7. PubMed PMID:36220816 PubMed Central PMC9553944.
  5. Montero-Odasso, M, van der Velde, N, Martin, FC, Petrovic, M, Tan, MP, Ryg, J et al.. World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing. 2022;51 (9):. doi: 10.1093/ageing/afac205. PubMed PMID:36178003 PubMed Central PMC9523684.
  6. Thomas, SM, Parker, A, Fortune, J, Mitchell, G, Hezam, A, Jiang, Y et al.. Global evidence on falls and subsequent social isolation in older adults: a scoping review. BMJ Open. 2022;12 (9):e062124. doi: 10.1136/bmjopen-2022-062124. PubMed PMID:36175106 PubMed Central PMC9528590.
  7. Seppala, LJ, Kamkar, N, van Poelgeest, EP, Thomsen, K, Daams, JG, Ryg, J et al.. Medication reviews and deprescribing as a single intervention in falls prevention: a systematic review and meta-analysis. Age Ageing. 2022;51 (9):. doi: 10.1093/ageing/afac191. PubMed PMID:36153749 PubMed Central PMC9509688.
  8. Atchison, K, Watt, JA, Ewert, D, Toohey, AM, Ismail, Z, Goodarzi, Z et al.. Non-pharmacologic and pharmacologic treatments for anxiety in long-term care: a systematic review and meta-analysis. Age Ageing. 2022;51 (9):. doi: 10.1093/ageing/afac195. PubMed PMID:36057989 .
  9. Tahir, UA, Katz, DH, Avila-Pachecho, J, Bick, AG, Pampana, A, Robbins, JM et al.. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022;13 (1):4923. doi: 10.1038/s41467-022-32275-3. PubMed PMID:35995766 PubMed Central PMC9395431.
  10. Lunny, C, Veroniki, AA, Hutton, B, White, I, Higgins, J, Wright, JM et al.. Knowledge user survey and Delphi process to inform development of a new risk of bias tool to assess systematic reviews with network meta-analysis (RoB NMA tool). BMJ Evid Based Med. 2023;28 (1):58-67. doi: 10.1136/bmjebm-2022-111944. PubMed PMID:35948412 .
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Affiliations & Other Activities

  • Geriatrician, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto