Research Programs

Biography

Research Interests

Multiple sclerosis (MS), MRI biomarkers with clinical utility in prognostication and disease monitoring, cohort studies

Research Activities

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local and multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS.

Recent Publications

  1. Spelman, T, Ozakbas, S, Alroughani, R, Terzi, M, Hodgkinson, S, Laureys, G et al.. Comparative effectiveness of cladribine tablets versus other oral disease-modifying treatments for multiple sclerosis: Results from MSBase registry. Mult Scler. 2022; :13524585221137502. doi: 10.1177/13524585221137502. PubMed PMID:36433775 .
  2. Kuhlmann, T, Moccia, M, Coetzee, T, Cohen, JA, Correale, J, Graves, J et al.. Multiple sclerosis progression: time for a new mechanism-driven framework. Lancet Neurol. 2022; :. doi: 10.1016/S1474-4422(22)00289-7. PubMed PMID:36410373 .
  3. Oh, J, Bar-Or, A. Ublituximab: a new anti-CD20 agent for multiple sclerosis. Lancet Neurol. 2022;21 (12):1070-1072. doi: 10.1016/S1474-4422(22)00446-X. PubMed PMID:36402153 .
  4. Schneider, R, Oh, J. Bruton's Tyrosine Kinase Inhibition in Multiple Sclerosis. Curr Neurol Neurosci Rep. 2022;22 (11):721-734. doi: 10.1007/s11910-022-01229-z. PubMed PMID:36301434 PubMed Central PMC9607648.
  5. Seyman, E, Kim, D, Bharatha, A, Casserly, C, Krysko, K, Chantal, RH et al.. Quantitative spinal cord MRI and sexual dysfunction in multiple sclerosis. Mult Scler J Exp Transl Clin. 2022;8 (4):20552173221132170. doi: 10.1177/20552173221132170. PubMed PMID:36277232 PubMed Central PMC9585573.
  6. Fauchon, C, Kim, JA, El-Sayed, R, Osborne, NR, Rogachov, A, Cheng, JC et al.. A Hidden Markov Model reveals magnetoencephalography spectral frequency-specific abnormalities of brain state power and phase-coupling in neuropathic pain. Commun Biol. 2022;5 (1):1000. doi: 10.1038/s42003-022-03967-9. PubMed PMID:36131088 PubMed Central PMC9492713.
  7. Daboul, L, O'Donnell, CM, Cao, Q, Amin, M, Rodrigues, P, Derbyshire, J et al.. Effect of GBCA Use on Detection and Diagnostic Performance of the Central Vein Sign: Evaluation Using a 3-T FLAIR* Sequence in Patients With Suspected Multiple Sclerosis. AJR Am J Roentgenol. 2022; :1-11. doi: 10.2214/AJR.22.27731. PubMed PMID:35975888 .
  8. Oh, J. Diagnosis of Multiple Sclerosis. Continuum (Minneap Minn). 2022;28 (4):1006-1024. doi: 10.1212/CON.0000000000001156. PubMed PMID:35938655 .
  9. Zhong, M, van der Walt, A, Monif, M, Hodgkinson, S, Eichau, S, Kalincik, T et al.. Prediction of relapse activity when switching to cladribine for multiple sclerosis. Mult Scler. 2022; :13524585221111677. doi: 10.1177/13524585221111677. PubMed PMID:35894247 .
  10. Ostrem, BL, Anderson, A, Conway, S, Healy, BC, Oh, J, Jacobs, D et al.. Peripartum disease activity in moderately and severely disabled women with multiple sclerosis. Mult Scler J Exp Transl Clin. 2022;8 (2):20552173221104918. doi: 10.1177/20552173221104918. PubMed PMID:35734229 PubMed Central PMC9208060.
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Affiliations & Other Activities

  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, University of Toronto
  • Adjunct Faculty, Department of Neurology, Johns Hopkins University