Research Programs

Biography

Research Interests

Multiple sclerosis (MS), MRI biomarkers with clinical utility in prognostication and disease monitoring, cohort studies

Research Activities

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local and multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS.

Recent Publications

  1. Sharmin, S, Roos, I, Malpas, CB, Iaffaldano, P, Simone, M, Filippi, M et al.. Disease-modifying therapies in managing disability worsening in paediatric-onset multiple sclerosis: a longitudinal analysis of global and national registries. Lancet Child Adolesc Health. 2024;8 (5):348-357. doi: 10.1016/S2352-4642(24)00047-6. PubMed PMID:38547883 .
  2. Levit, E, Ren, Z, Gonzenbach, V, Azevedo, CJ, Calabresi, PA, Cree, BA et al.. Choroid plexus volume differentiates MS from its mimics. Mult Scler. 2024; :13524585241238094. doi: 10.1177/13524585241238094. PubMed PMID:38481081 .
  3. Lim, TRU, Kumaran, SP, Suthiphosuwan, S, Espiritu, AI, Jones, A, Lin, AW et al.. Limited utility of adding 3T cervical spinal cord MRI to monitor disease activity in multiple sclerosis. Mult Scler. 2024;30 (4-5):505-515. doi: 10.1177/13524585241228426. PubMed PMID:38419027 .
  4. Bagnato, F, Sati, P, Hemond, CC, Elliott, C, Gauthier, SA, Harrison, DM et al.. Imaging chronic active lesions in multiple sclerosis: a consensus statement. Brain. 2024; :. doi: 10.1093/brain/awae013. PubMed PMID:38226694 .
  5. Oh, J, Capezzuto, L, Kriara, L, Schjodt-Eriksen, J, van Beek, J, Bernasconi, C et al.. Use of smartphone-based remote assessments of multiple sclerosis in Floodlight Open, a global, prospective, open-access study. Sci Rep. 2024;14 (1):122. doi: 10.1038/s41598-023-49299-4. PubMed PMID:38168498 PubMed Central PMC10762023.
  6. Schneider, R, Brand-Arzamendi, K, Reynold Lim, T, Lee, LE, Guenette, M, Suthiphosuwan, S et al.. Plasma glial fibrillary acidic protein levels correlate with paramagnetic rim lesions in people with radiologically isolated syndrome. Mult Scler. 2024;30 (2):156-165. doi: 10.1177/13524585231219131. PubMed PMID:38145319 .
  7. Oh, J, Airas, L, Harrison, D, Järvinen, E, Livingston, T, Lanker, S et al.. Neuroimaging to monitor worsening of multiple sclerosis: advances supported by the grant for multiple sclerosis innovation. Front Neurol. 2023;14 :1319869. doi: 10.3389/fneur.2023.1319869. PubMed PMID:38107636 PubMed Central PMC10722910.
  8. Daboul, L, O'Donnell, CM, Amin, M, Rodrigues, P, Derbyshire, J, Azevedo, C et al.. A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis. Mult Scler. 2024;30 (1):25-34. doi: 10.1177/13524585231214360. PubMed PMID:38088067 .
  9. Chertcoff, A, Schneider, R, Azevedo, CJ, Sicotte, N, Oh, J. Recent Advances in Diagnostic, Prognostic, and Disease-Monitoring Biomarkers in Multiple Sclerosis. Neurol Clin. 2024;42 (1):15-38. doi: 10.1016/j.ncl.2023.06.008. PubMed PMID:37980112 .
  10. Greenfield, J, Metz, LM, Khakban, A, Llorian, ER, Michaux, KD, Traboulsee, A et al.. Cancer risk, disease-modifying therapy, and age in multiple sclerosis: A retrospective population-based cohort study. Mult Scler Relat Disord. 2023;80 :105091. doi: 10.1016/j.msard.2023.105091. PubMed PMID:37924714 .
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Affiliations & Other Activities

  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, University of Toronto
  • Adjunct Faculty, Department of Neurology, Johns Hopkins University