Research Programs


Research Interests

Multiple sclerosis (MS), MRI biomarkers with clinical utility in prognostication and disease monitoring, cohort studies

Research Activities

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local and multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS.

Recent Publications

  1. Li, Y, Saul, A, Taylor, B, Ponsonby, AL, Simpson-Yap, S, Blizzard, L et al.. Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis: recruitment challenges, potential bias, and statistical strategies. J Neurol. 2023; :. doi: 10.1007/s00415-023-11980-z. PubMed PMID:37768389 .
  2. Hector, MS, Cheng, JC, Hemington, KS, Rogachov, A, Kim, JA, Osborne, NR et al.. Resilience is associated with cortical gray matter of the antinociceptive pathway in people with chronic pain. Biol Psychol. 2023;183 :108658. doi: 10.1016/j.biopsycho.2023.108658. PubMed PMID:37567549 .
  3. Kalincik, T, Sharmin, S, Roos, I, Freedman, MS, Atkins, H, Burman, J et al.. Comparative Effectiveness of Autologous Hematopoietic Stem Cell Transplant vs Fingolimod, Natalizumab, and Ocrelizumab in Highly Active Relapsing-Remitting Multiple Sclerosis. JAMA Neurol. 2023;80 (7):702-713. doi: 10.1001/jamaneurol.2023.1184. PubMed PMID:37437240 PubMed Central PMC10186210.
  4. Sharmin, S, Roos, I, Simpson-Yap, S, Malpas, C, Sánchez, MM, Ozakbas, S et al.. The risk of secondary progressive multiple sclerosis is geographically determined but modifiable. Brain. 2023; :. doi: 10.1093/brain/awad218. PubMed PMID:37369086 .
  5. Hobart, J, Chitnis, T, Oh, J, Burke, L, King, M, Vo, P et al.. Do clinical trials prepare to fail by failing to prepare? An examination of MS trials and recommendations for patient-reported outcome measure selection. Mult Scler Relat Disord. 2023;76 :104788. doi: 10.1016/j.msard.2023.104788. PubMed PMID:37327599 .
  6. Roos, I, Hughes, S, McDonnell, G, Malpas, CB, Sharmin, S, Boz, C et al.. Rituximab vs Ocrelizumab in Relapsing-Remitting Multiple Sclerosis. JAMA Neurol. 2023;80 (8):789-797. doi: 10.1001/jamaneurol.2023.1625. PubMed PMID:37307006 PubMed Central PMC10262062.
  7. Spelman, T, Ozakbas, S, Alroughani, R, Terzi, M, Hodgkinson, S, Laureys, G et al.. A plain language summary on the effectiveness of cladribine tablets compared with other oral treatments for multiple sclerosis: results from the MSBase registry. Neurodegener Dis Manag. 2023;13 (4):215-221. doi: 10.2217/nmt-2023-0005. PubMed PMID:37287269 .
  8. Harding-Forrester, S, Roos, I, Nguyen, AL, Malpas, CB, Diouf, I, Moradi, N et al.. Disability accrual in primary and secondary progressive multiple sclerosis. J Neurol Neurosurg Psychiatry. 2023;94 (9):707-717. doi: 10.1136/jnnp-2022-330726. PubMed PMID:37068931 .
  9. Giacomini, PS, Oh, J, Morrow, SA, Beauchemin, P, Clift, F, Devonshire, V et al.. Virtual Management of Multiple Sclerosis: Providing Access or Just Phoning it in?. Can J Neurol Sci. 2023; :1-4. doi: 10.1017/cjn.2023.41. PubMed PMID:37066757 .
  10. Rodriguez Llorian, E, Zhang, W, Khakban, A, Michaux, K, Patten, S, Traboulsee, A et al.. Employment status, productivity loss, and associated factors among people with multiple sclerosis. Mult Scler. 2023;29 (7):866-874. doi: 10.1177/13524585231164295. PubMed PMID:37060245 PubMed Central PMC10278386.
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Affiliations & Other Activities

  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, University of Toronto
  • Adjunct Faculty, Department of Neurology, Johns Hopkins University