Jose Danilo Diestro


Investigator, Li Ka Shing Knowledge Institute


Dr. Jose Danilo B. Diestro is a vascular neurologist with subspecialty training in interventional neuroradiology working as a staff physician at St. Michael’s Hospital and an investigator at the Li Ka Shing Knowledge Institute. He holds the rank of Assistant Professor at the University of Toronto, Department of Medicine, Division of Neurology as a Clinician Investigator. He received academic training from the University of the Philippines (Doctor of Medicine, Adult Neurology Residency, Stroke Fellowship), University of Toronto and Université de Montréal (Interventional Neuroradiology Fellowships) and, McMaster University (Master of Science in Health Research Methodology- Clinical Epidemiology).

His clinical research is dedicated to three key areas: 1) exploring outcomes and decision-making in endovascular stroke treatment, 2) investigating innovative devices for aneurysm treatment, and 3) studying the long-term clinical consequences of subarachnoid hemorrhage. His overarching goal is to impact clinical practice by actively participating in and leading randomized controlled trials.

Recent Publications

  1. Kühn, AL, Puri, AS, Salim, HA, Musmar, B, Ghozy, S, Siegler, J et al.. Multicenter evaluation of mechanical thrombectomy for distal medium vessel occlusions with National Institute of Health Stroke Scale Scores ≥ 6 and ≤ 6. J Neurol. 2024; :. doi: 10.1007/s00415-024-12537-4. PubMed PMID:38967650 .
  2. Omar, AT, Diestro, JDB, Spears, J, Patorno, E. Treatment modality for aneurysmal subarachnoid hemorrhage and risk of shunt dependent hydrocephalus and mortality: population based study. J Neurointerv Surg. 2024; :. doi: 10.1136/jnis-2024-021852. PubMed PMID:38839284 .
  3. Diestro, JDB, Adeeb, N, Musmar, B, Salim, H, Aslan, A, Cancelliere, NM et al.. Association of preprocedural antiplatelet use with decreased thromboembolic complications for intracranial aneurysms undergoing intrasaccular flow disruption. J Neurosurg. 2024; :1-8. doi: 10.3171/2024.2.JNS232918. PubMed PMID:38701528 .
  4. Ignacio, KHD, Muir, RT, Diestro, JDB, Singh, N, Yu, MHLL, Omari, OE et al.. Prevalence of depression and anxiety symptoms after stroke in young adults: A systematic review and meta-analysis. J Stroke Cerebrovasc Dis. 2024;33 (7):107732. doi: 10.1016/j.jstrokecerebrovasdis.2024.107732. PubMed PMID:38657829 .
  5. Diestro, JDB, Vyas, M, Jung, Y, Kishibe, T, Leochico, C, Espiritu, A et al.. Long-term neuropsychiatric complications of aneurysmal subarachnoid hemorrhage: a narrative review. J Neurointerv Surg. 2024; :. doi: 10.1136/jnis-2023-020979. PubMed PMID:38609175 .
  6. Dmytriw, AA, Salim, H, Musmar, B, Aslan, A, Cancelliere, NM, McLellan, RM et al.. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis. Neurosurg Rev. 2024;47 (1):116. doi: 10.1007/s10143-024-02341-z. PubMed PMID:38483647 .
  7. Diestro, JDB, Fahed, R, Omar, AT, Hawkes, C, Hendriks, EJ, Enriquez, C et al.. Clinical uncertainty in large vessel occlusion ischemic stroke: does automated perfusion imaging make a difference? An intra-rater and inter-rater agreement study. J Neurointerv Surg. 2024; :. doi: 10.1136/jnis-2023-021429. PubMed PMID:38453461 .
  8. Boisseau, W, Benomar, A, Ducroux, C, Fahed, R, Smajda, S, Diestro, JDB et al.. The Management of Persistent Distal Occlusions after Mechanical Thrombectomy and Thrombolysis: An Inter- and Intrarater Agreement Study. AJNR Am J Neuroradiol. 2024; :. doi: 10.3174/ajnr.A8149. PubMed PMID:38388684 .
  9. Benomar, A, Diestro, JDB, Darabid, H, Saydy, K, Tzaneva, L, Li, J et al.. Nonaneurysmal perimesencephalic subarachnoid hemorrhage on noncontrast head CT: An accuracy, inter-rater, and intra-rater reliability study. J Neuroradiol. 2024;51 (4):101184. doi: 10.1016/j.neurad.2024.02.002. PubMed PMID:38387650 .
  10. Wang, M, Henkes, H, Ghozy, S, Siegler, JE, Shaikh, H, Khalife, J et al.. Use of the pRESET LITE thrombectomy device in combined approach for medium vessel occlusions: A multicenter evaluation. Neuroradiology. 2024;66 (4):631-641. doi: 10.1007/s00234-024-03302-5. PubMed PMID:38381145 .
Search PubMed

Affiliations & Other Activities

  • Assistant Professor, Department of Medicine, University of Toronto