Kamel Kamel

FRCP(C), MB BCh

Investigator

Biography

Research Interests

Dysnatremias, dyskalemias, metabolic acidosis, metabolic alkalosis, nephrolithiasis

Research Activities

1. Clinical disorders of fluid and electrolytes and acid-base balance
2. Metabolic regulation and acid-base balance
3. Pathophysiology of nephrolithiasis

Recent Publications

  1. Kamel, KS, Shapiro, J, Harel, Z. A 23-year-old woman with metabolic alkalosis and hypokalemia. CMAJ. 2024;196 (22):E760-E764. doi: 10.1503/cmaj.240163. PubMed PMID:38857937 PubMed Central PMC11173655.
  2. Sterns, RH, Rondon-Berrios, H, Adrogué, HJ, Berl, T, Burst, V, Cohen, DM et al.. Treatment Guidelines for Hyponatremia: Stay the Course. Clin J Am Soc Nephrol. 2023;19 (1):129-35. doi: 10.2215/CJN.0000000000000244. PubMed PMID:37379081 PubMed Central PMC10843202.
  3. Kamel, KS, Schreiber, M, Harel, Z. Hypernatremia. JAMA. 2022;327 (8):774-775. doi: 10.1001/jama.2022.1376. PubMed PMID:35191944 .
  4. Kamel, KS, Halperin, ML. Use of Urine Electrolytes and Urine Osmolality in the Clinical Diagnosis of Fluid, Electrolytes, and Acid-Base Disorders. Kidney Int Rep. 2021;6 (5):1211-1224. doi: 10.1016/j.ekir.2021.02.003. PubMed PMID:34013099 PubMed Central PMC8116912.
  5. Kamel, KS, Oh, MS, Halperin, ML. L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. Kidney Int. 2020;97 (1):75-88. doi: 10.1016/j.kint.2019.08.023. PubMed PMID:31784049 .
  6. Kamel, KS, Carlotti, APCP, Halperin, ML. Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018;379 (12):1181-2. doi: 10.1056/NEJMc1810064. PubMed PMID:30260149 .
  7. Kamel, KS. Diagnostic Use of Base Excess in Acid-Base Disorders. N Engl J Med. 2018;379 (5):495-6. doi: 10.1056/NEJMc1806372. PubMed PMID:30070104 .
  8. Kamel, KS, Schreiber, M, Halperin, ML. Renal potassium physiology: integration of the renal response to dietary potassium depletion. Kidney Int. 2018;93 (1):41-53. doi: 10.1016/j.kint.2017.08.018. PubMed PMID:29102372 .
  9. Kamel, KS, Schreiber, M, Carlotti, AP, Halperin, ML. Approach to the Treatment of Diabetic Ketoacidosis. Am J Kidney Dis. 2016;68 (6):967-972. doi: 10.1053/j.ajkd.2016.05.034. PubMed PMID:27599629 .
  10. Harel, Z, Kamel, KS. Optimal Dose and Method of Administration of Intravenous Insulin in the Management of Emergency Hyperkalemia: A Systematic Review. PLoS One. 2016;11 (5):e0154963. doi: 10.1371/journal.pone.0154963. PubMed PMID:27148740 PubMed Central PMC4857926.
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Affiliations & Other Activities

  • Staff Physician, Division of Nephrology, Department of Medicine, St. Michael’s Hospital
  • Professor, Department of Medicine, University of Toronto