Sheldon Cheskes




Dr. Sheldon Cheskes is a Professor with the Division of Emergency Medicine, Department of Family and Community Medicine at the University of Toronto and a Scientist at the Li Ka Shing Knowledge Institute at St. Michael’s Hospital, Unity Health Toronto. He is the Medical Director for the Regions of Halton and Peel with the Sunnybrook Centre for Prehospital Medicine and Affiliate Scientist with the Sunnybrook Research Institute in Toronto. He is the Co-Principal Investigator for the Resuscitation Repository & Research Database (R3DB), one of the Principal Investigators for the Canadian Resuscitation Outcomes Consortium (CanROC). Dr. Cheskes is a recognized international leader in the area of CPR quality and out-of-hospital cardiac arrest resuscitation and his work transcends research into clinical practice. He is a mentor to many in the field across prehospital care and resuscitation. Dr. Cheskes has published over 140 manuscripts in high impact journals, such as the New England Journal of Medicine, Circulation, CMAJ and Resuscitation that have changed resuscitation practice around the world.

He is the principal investigator of the recently published DOuble Sequential External Defibrillation in Refractory Ventricular Fibrillation (DOSE VF) trial exploring alternate defibrillation strategies for refractory ventricular fibrillation during out-of-hospital cardiac arrest.


Recent Publications

  1. Feldman, M, Bahaidarah, F, Rahimi, M, Howaidi, S, Turner, L, Verbeek, PR et al.. Safety and adverse events during primary care paramedic interfacility transfer of stable STEMI patients. Prehosp Emerg Care. 2024; :1-9. doi: 10.1080/10903127.2024.2342569. PubMed PMID:38619868 .
  2. Brent, CM, Cheskes, S, Castrén, M, Brooks, SC. Erratum to "Wolf Creek XVII Part 5: Mobile AEDs" [Resusc. Plus 16 (2023) 100500]. Resusc Plus. 2024;17 :100579. doi: 10.1016/j.resplu.2024.100579. PubMed PMID:38586862 PubMed Central PMC10995635.
  3. Cheskes, S, Drennan, IR, Turner, L, Pandit, SV, Dorian, P. The impact of alternate defibrillation strategies on shock-refractory and recurrent ventricular fibrillation: A secondary analysis of the DOSE VF cluster randomized controlled trial. Resuscitation. 2024; :110186. doi: 10.1016/j.resuscitation.2024.110186. PubMed PMID:38522736 .
  4. Deb, S, Drennan, I, Turner, L, Cheskes, S. Association of coronary angiography with ST-elevation and no ST-elevation in patients with refractory ventricular fibrillation - A substudy of the DOuble SEquential External Defibrillation for Refractory Ventricular Fibrillation (DOSE-VF randomized control trial). Resuscitation. 2024; :110163. doi: 10.1016/j.resuscitation.2024.110163. PubMed PMID:38447909 .
  5. Drennan, IR, McLeod, SL, Cheskes, S. Randomized controlled trials in resuscitation. Resusc Plus. 2024;18 :100582. doi: 10.1016/j.resplu.2024.100582. PubMed PMID:38444863 PubMed Central PMC10912727.
  6. Zègre-Hemsey, JK, Cheskes, S, Johnson, AM, Rosamond, WD, Cunningham, CJ, Arnold, E et al.. Challenges & barriers for real-time integration of drones in emergency cardiac care: Lessons from the United States, Sweden, & Canada. Resusc Plus. 2024;17 :100554. doi: 10.1016/j.resplu.2024.100554. PubMed PMID:38317722 PubMed Central PMC10838948.
  7. Rahimi, M, Drennan, IR, Turner, L, Dorian, P, Cheskes, S. The impact of double sequential shock timing on outcomes during refractory out-of-hospital cardiac arrest. Resuscitation. 2024;194 :110082. doi: 10.1016/j.resuscitation.2023.110082. PubMed PMID:38092182 .
  8. Yap, J, Kayda, I, Asamoah-Boaheng, M, Haig, S, Kirkham, T, Cheskes, S et al.. The relationship between the number of COVID-19 vaccines and infection with Omicron ACE2 inhibition at 18-months post initial vaccination in an adult cohort of Canadian paramedics. Access Microbiol. 2023;5 (11):. doi: 10.1099/acmi.0.000725.v3. PubMed PMID:38074102 PubMed Central PMC10702377.
  9. Brent, CM, Cheskes, S, Castrén, M, Brooks, SC. Wolf Creek XVII Part 5: Mobile AEDs. Resusc Plus. 2023;16 :100500. doi: 10.1016/j.resplu.2023.100500. PubMed PMID:38033344 PubMed Central PMC10685038.
  10. Drennan, IR, Thorpe, KE, Scales, D, Cheskes, S, Mamdani, M, Morrison, LJ et al.. Predicting survival post-cardiac arrest: An observational cohort study. Resusc Plus. 2023;15 :100447. doi: 10.1016/j.resplu.2023.100447. PubMed PMID:37662643 PubMed Central PMC10470201.
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Affiliations & Other Activities

  • Associate Professor, Department of Family and Community Medicine, Division of Emergency Medicine, University of Toronto
  • Medical Director, Sunnybrook Centre for Prehospital Medicine