Biography

Dr. Schweizer’s area of interest is in Cognitive Neuroscience and Neuroimaging, focusing on understanding the neural bases for human cognitive and real-world functioning using experimental cognitive paradigms, neuroimaging and neuropsychology. A better understanding of the complex neural systems supporting various cognitive and real-world functions and their breakdown after brain damage (e.g. Stroke, Traumatic Brain Injury, Alzheimer’s Disease) is essential in educating physicians, patients and families and critical in designing effective treatment strategies. Dr. Schweizer and his team have developed a novel and fully immersive driving simulator and touch tablet placed in a 3.0 Tesla functional magnetic resonance imaging (fMRI) system. The MRI compatible equipment can capture brain activity during real world tasks. Dr. Schweizer and his group are also investigating novel approaches to image processing and data analysis in functional neuroimaging, in order to improve the reliability and interpretability of fMRI findings, particularly in clinical and aging populations. Dr. Schweizer is an Ontario Early Researcher Award holder and is supported by a New Investigator Award from the Heart and Stroke Foundation of Canada and research awards from the Ministry of Transportation Ontario and other National peer-reviewed funding agencies including Canadian Institutes for Health Research.

Recent Publications

  1. Fischer, CE, Namasivayam, A, Crawford-Holland, L, Hakobyan, N, Schweizer, TA, Munoz, DG et al.. Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment. Psychiatr Clin North Am. 2022;45 (4):691-705. doi: 10.1016/j.psc.2022.07.001. PubMed PMID:36396273 .
  2. Dissanayake, AS, Tan, YB, Bowie, CR, Butters, MA, Flint, AJ, Gallagher, D et al.. Sex Modifies the Associations of APOEɛ4 with Neuropsychiatric Symptom Burden in Both At-Risk and Clinical Cohorts of Alzheimer's Disease. J Alzheimers Dis. 2022; :. doi: 10.3233/JAD-220586. PubMed PMID:36314203 .
  3. Valcic, M, Khoury, MA, Kim, J, Fornazzari, L, Churchill, NW, Ismail, Z et al.. Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort. Brain Sci. 2022;12 (9):. doi: 10.3390/brainsci12091266. PubMed PMID:36139002 PubMed Central PMC9497154.
  4. Khoury, MA, Bahsoun, MA, Fadhel, A, Shunbuli, S, Venkatesh, S, Ghazvanchahi, A et al.. Delusional Severity Is Associated with Abnormal Texture in FLAIR MRI. Brain Sci. 2022;12 (5):. doi: 10.3390/brainsci12050600. PubMed PMID:35624987 PubMed Central PMC9139341.
  5. Atayde, AL, Fischer, CE, Schweizer, TA, Munoz, DG. Neuropsychiatric Inventory-Questionnaire Assessed Nighttime Behaviors in Cognitively Asymptomatic Patients with Pathologically Confirmed Alzheimer's Disease Predict More Rapid Cognitive Deterioration. J Alzheimers Dis. 2022;86 (3):1137-1147. doi: 10.3233/JAD-215276. PubMed PMID:35180114 PubMed Central PMC9664561.
  6. Anteraper, SA, Guell, X, Lee, YJ, Raya, J, Demchenko, I, Churchill, NW et al.. Cerebello-cerebral Functional Connectivity Networks in Major Depressive Disorder: a CAN-BIND-1 Study Report. Cerebellum. 2022; :. doi: 10.1007/s12311-021-01353-5. PubMed PMID:35023065 .
  7. Churchill, NW, Di Battista, AP, Rhind, SG, Richards, D, Schweizer, TA, Hutchison, MG et al.. Cerebral blood flow is associated with matrix metalloproteinase levels during the early symptomatic phase of concussion. PLoS One. 2021;16 (11):e0253134. doi: 10.1371/journal.pone.0253134. PubMed PMID:34727098 PubMed Central PMC8562781.
  8. Churchill, NW, Hutchison, MG, Graham, SJ, Schweizer, TA. Sex differences in acute and long-term brain recovery after concussion. Hum Brain Mapp. 2021;42 (18):5814-5826. doi: 10.1002/hbm.25591. PubMed PMID:34643005 PubMed Central PMC8596946.
  9. Fischer, CE, Churchill, N, Leggieri, M, Vuong, V, Tau, M, Fornazzari, LR et al.. Long-Known Music Exposure Effects on Brain Imaging and Cognition in Early-Stage Cognitive Decline: A Pilot Study. J Alzheimers Dis. 2021;84 (2):819-833. doi: 10.3233/JAD-210610. PubMed PMID:34602475 .
  10. Yuen, NH, Tam, F, Churchill, NW, Schweizer, TA, Graham, SJ. Driving With Distraction: Measuring Brain Activity and Oculomotor Behavior Using fMRI and Eye-Tracking. Front Hum Neurosci. 2021;15 :659040. doi: 10.3389/fnhum.2021.659040. PubMed PMID:34483861 PubMed Central PMC8415783.
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Affiliations & Other Activities

  • Scientist, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital
  • Associate Professor, Faculty of Medicine (Neurosurgery), University of Toronto
  • Associate Professor, Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto