Ziv Harel

MD, MSc

Investigator

Biography

Ziv Harel is a nephrologist and Associate Professor of Medicine at the University of Toronto. He completed his undergraduate degrees at the University of Toronto, medical school at the University of Western Ontario, and continued his clinical training in internal medicine and nephrology at the University of Toronto. Following this, he completed a Master’s degree in Clinical Epidemiology at the University of Toronto, a research fellowship at Women’s College Hospital, and the Veteran’s Health Administration Quality Scholars (VAQS) Fellowship in patient safety. In addition to attending on the hospital’s Nephrology consult and ward services, Dr. Harel provides longitudinal care for patients on chronic hemodialysis and has an active general nephrology practice.

Dr. Harel’s research interests are in the areas of anticoagulation in patients receiving dialysis, the interplay of pregnancy and the kidney, and patient safety in individuals with chronic kidney disease. He is currently leading a Canadian Institutes of Health Research-funded international trial on the role of oral anticoagulation in patients with atrial fibrillation receiving chronic dialysis. As a founding member of the Kidney Dialysis and Transplantation Program at ICES, Dr. Harel is also involved in several studies that are using province-wide population-based data to answer research questions in kidney disease.

Recent Publications

  1. Wing, SM, Mavrakanas, TA, Harel, Z. Oral Anticoagulation Use in Individuals With Atrial Fibrillation and Chronic Kidney Disease: A Review. Semin Nephrol. 2024; :151517. doi: 10.1016/j.semnephrol.2024.151517. PubMed PMID:38744617 .
  2. Harel, Z, Jeyakumar, N, Kang, Y, Velez, MP, Dayan, N, Ray, JG et al.. Periconceptional Serum Creatinine and Risk of Childhood Autism Spectrum Disorder: A Research Letter. Can J Kidney Health Dis. 2024;11 :20543581231221892. doi: 10.1177/20543581231221892. PubMed PMID:38161392 PubMed Central PMC10757427.
  3. Ray, JG, Harel, Z, Gilbert, RE, Wald, R, Berger, H, Park, AL et al.. Preconception SGLT2 or DPP4 inhibitor use and adverse pregnancy outcomes. Diabetes Res Clin Pract. 2023;205 :110946. doi: 10.1016/j.diabres.2023.110946. PubMed PMID:37813164 .
  4. Ha, JT, Scaria, A, Andrade, J, Badve, SV, Birks, P, Bota, SE et al.. Safety and Effectiveness of Rivaroxaban Versus Warfarin Across GFR Levels in Atrial Fibrillation: A Population-Based Study in Australia and Canada. Kidney Med. 2023;5 (7):100675. doi: 10.1016/j.xkme.2023.100675. PubMed PMID:37492112 PubMed Central PMC10363562.
  5. Yau, K, Jeyakumar, N, Kang, Y, Dixon, SN, Freeman, M, Garg, AX et al.. Association of Primary Versus Rotating Nephrologist Model of Care in Hemodialysis Programs with Patient Outcomes. J Am Soc Nephrol. 2023;34 (7):1155-1158. doi: 10.1681/ASN.0000000000000133. PubMed PMID:37022115 PubMed Central PMC10356167.
  6. Meraz-Muñoz, AY, Jeyakumar, N, Luo, B, Beaubien-Souligny, W, Chanchlani, R, Clark, EG et al.. Cardiovascular Drug Use After Acute Kidney Injury Among Hospitalized Patients With a History of Myocardial Infarction. Kidney Int Rep. 2023;8 (2):294-304. doi: 10.1016/j.ekir.2022.10.027. PubMed PMID:36815105 PubMed Central PMC9939314.
  7. Tangren, J, Bathini, L, Jeyakumar, N, Dixon, SN, Ray, J, Wald, R et al.. Pre-Pregnancy eGFR and the Risk of Adverse Maternal and Fetal Outcomes: A Population-Based Study. J Am Soc Nephrol. 2023;34 (4):656-667. doi: 10.1681/ASN.0000000000000053. PubMed PMID:36735377 PubMed Central PMC10103349.
  8. Silver, SA, Adhikari, NK, Jeyakumar, N, Luo, B, Harel, Z, Dixon, SN et al.. Association of an Acute Kidney Injury Follow-up Clinic With Patient Outcomes and Care Processes: A Cohort Study. Am J Kidney Dis. 2023;81 (5):554-563.e1. doi: 10.1053/j.ajkd.2022.10.011. PubMed PMID:36521779 .
  9. Perl, J, Harel, Z, Nessim, SJ. Peritoneal Fluid Analysis in Peritoneal Dialysis-Associated Peritonitis. JAMA. 2022; :. doi: 10.1001/jama.2022.21289. PubMed PMID:36355384 .
  10. Jun, M, Scaria, A, Andrade, J, Badve, SV, Birks, P, Bota, SE et al.. Kidney function and the comparative effectiveness and safety of direct oral anticoagulants vs. warfarin in adults with atrial fibrillation: a multicenter observational study. Eur Heart J Qual Care Clin Outcomes. 2023;9 (6):621-631. doi: 10.1093/ehjqcco/qcac069. PubMed PMID:36302143 .
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Affiliations & Other Activities

  • Adjunct Scientist, ICES