Ziv Harel

MD, MSc

Investigator

Biography

Ziv Harel is a nephrologist and Associate Professor of Medicine at the University of Toronto. He completed his undergraduate degrees at the University of Toronto, medical school at the University of Western Ontario, and continued his clinical training in internal medicine and nephrology at the University of Toronto. Following this, he completed a Master’s degree in Clinical Epidemiology at the University of Toronto, a research fellowship at Women’s College Hospital, and the Veteran’s Health Administration Quality Scholars (VAQS) Fellowship in patient safety. In addition to attending on the hospital’s Nephrology consult and ward services, Dr. Harel provides longitudinal care for patients on chronic hemodialysis and has an active general nephrology practice.

Dr. Harel’s research interests are in the areas of anticoagulation in patients receiving dialysis, the interplay of pregnancy and the kidney, and patient safety in individuals with chronic kidney disease. He is currently leading a Canadian Institutes of Health Research-funded international trial on the role of oral anticoagulation in patients with atrial fibrillation receiving chronic dialysis. As a founding member of the Kidney Dialysis and Transplantation Program at ICES, Dr. Harel is also involved in several studies that are using province-wide population-based data to answer research questions in kidney disease.

Recent Publications

  1. Tangren, J, Bathini, L, Jeyakumar, N, Dixon, SN, Ray, J, Wald, R et al.. Pre-Pregnancy eGFR and the Risk of Adverse Maternal and Fetal Outcomes: A Population-Based Study. J Am Soc Nephrol. 2023; :. doi: 10.1681/ASN.0000000000000053. PubMed PMID:36735377 .
  2. Silver, SA, Adhikari, NK, Jeyakumar, N, Luo, B, Harel, Z, Dixon, SN et al.. Association of an Acute Kidney Injury Follow-up Clinic With Patient Outcomes and Care Processes: A Cohort Study. Am J Kidney Dis. 2022; :. doi: 10.1053/j.ajkd.2022.10.011. PubMed PMID:36521779 .
  3. Perl, J, Harel, Z, Nessim, SJ. Peritoneal Fluid Analysis in Peritoneal Dialysis-Associated Peritonitis. JAMA. 2022; :. doi: 10.1001/jama.2022.21289. PubMed PMID:36355384 .
  4. Jun, M, Scaria, A, Andrade, J, Badve, SV, Birks, P, Bota, SE et al.. Kidney function and the comparative effectiveness and safety of direct oral anticoagulants versus warfarin in adults with atrial fibrillation: a multicenter observational study. Eur Heart J Qual Care Clin Outcomes. 2022; :. doi: 10.1093/ehjqcco/qcac069. PubMed PMID:36302143 .
  5. Harel, Z, Jeyakumar, N, Luo, B, Silver, SA, Akbari, A, Molnar, AO et al.. The Safety of Direct Oral Anticoagulants Versus Warfarin Among Older Individuals With Acute Venous Thromboembolism and CKD: A Population-Based Cohort Study. Kidney Med. 2022;4 (9):100516. doi: 10.1016/j.xkme.2022.100516. PubMed PMID:36147201 PubMed Central PMC9485588.
  6. Somaili, M, Jeyakumar, N, McArthur, E, Ribic, C, Sood, MM, Harel, Z et al.. Corrigendum to < Incidence of Direct Oral Anticoagulant Prescriptions in Kidney Transplant Recipients in Ontario, Canada> <[2020 Dec;52(10):3144-3152]>. Transplant Proc. 2022; :. doi: 10.1016/j.transproceed.2022.05.001. PubMed PMID:35725597 .
  7. Madan, S, Norman, PA, Wald, R, Neyra, JA, Meraz-Muñoz, A, Harel, Z et al.. Use of Guideline-Based Therapy for Diabetes, Coronary Artery Disease, and Chronic Kidney Disease After Acute Kidney Injury: A Retrospective Observational Study. Can J Kidney Health Dis. 2022;9 :20543581221103682. doi: 10.1177/20543581221103682. PubMed PMID:35721395 PubMed Central PMC9201307.
  8. Hill, K, Sucha, E, Rhodes, E, Bota, S, Hundemer, GL, Clark, EG et al.. Amiodarone, Verapamil, or Diltiazem Use With Direct Oral Anticoagulants and the Risk of Hemorrhage in Older Adults. CJC Open. 2022;4 (3):315-323. doi: 10.1016/j.cjco.2021.11.002. PubMed PMID:35386137 PubMed Central PMC8978070.
  9. Kamel, KS, Schreiber, M, Harel, Z. Hypernatremia. JAMA. 2022;327 (8):774-775. doi: 10.1001/jama.2022.1376. PubMed PMID:35191944 .
  10. Harel, Z, Park, AL, Ray, JG. Association Between Blunted Glomerular Hyperfiltration in Pregnancy and Severe Maternal Morbidity-A Research Letter. Can J Kidney Health Dis. 2021;8 :20543581211035221. doi: 10.1177/20543581211035221. PubMed PMID:34721883 PubMed Central PMC8552384.
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Affiliations & Other Activities

  • Adjunct Scientist, ICES