Subodh Verma

MD, PhD, FRCSC, FAHA

Scientist

Biography

Please note: Dr. Verma will not take students in summer.

Dr. Subodh Verma is an internationally renowned cardiac surgeon-scientist and Professor at the University of Toronto. He is the current Canada Research Chair in Cardiovascular Surgery, having previously served as the Canada Research Chair in Atherosclerosis (2007-2017). Dr. Verma was recently awarded the 2021 Lister Prize in Surgery from the University of Toronto in recognition of his outstanding and continuing productivity of international stature. He is a past recipient of the Howard Morgan Award for Distinguished Achievements in Cardiovascular Research and the Royal College of Physicians and Surgeons of Canada Gold Medal in Surgery. He is an appointee of the American Association of Thoracic Surgeons (AATS) and a member of the College of New Scholars, Artists and Scientists, Royal Society of Canada. According to Google Scholar in April 2021, Dr. Verma has an h-index of 100 and his work has been cited over 50,000 times.

Dr. Verma has published extensively in highly impactful journals like the NEJM, Lancet, Circulation, JACC, Nature, and JCI. He is an Associate Editor of the European Heart Journal. Dr. Verma is an active contributor to Canadian clinical practice guidelines and co-authored the recently updated recommendations for atrial fibrillation, antiplatelet therapy, diabetes, and heart failure; he was a member of the 2018 AATS consensus guidelines committee on bicuspid aortic valve-related aortopathy. Dr. Verma has served in various capacities on the American Heart Association Council on Cardiovascular Surgery and Anesthesia since 2008.

Dr. Verma had/has leadership roles on 10 contemporary global heart failure trials – several of which have let to paradigm changes in how individuals all around the world who live with diabetes and heart failure are now managed. He founded and oversees the CardioLink platform at St Michael’s Hospital that is conducting cardiometabolic and surgically oriented RCTs and translational studies.

Dr. Verma leads a dynamic pre-clinical and translational research team that leverages pre-clinical disease models and clinical trial-derived data to identify novel mediators of cardiovascular and cardiometabolic disease as well as answer timely and relevant healthcare questions. His research has yielded 2 United States patents and is supported by several national peer-reviewed grants.

 

Recent Publications

  1. Verma, S, Leiter, LA, Mangla, KK, Nielsen, NF, Hansen, Y, Bonaca, MP et al.. Epidemiology and Burden of Peripheral Artery Disease in People With Type 2 Diabetes: A Systematic Literature Review. Diabetes Ther. 2024; :. doi: 10.1007/s13300-024-01606-6. PubMed PMID:39023686 .
  2. Yang, M, Kondo, T, Jhund, PS, Alcocer-Gamba, MA, Borleffs, CJW, Chiang, CE et al.. Geographical variation in patient characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction. Eur J Heart Fail. 2024; :. doi: 10.1002/ejhf.3352. PubMed PMID:38923118 .
  3. Schou, M, Petrie, MC, Borlaug, BA, Butler, J, Davies, MJ, Kitzman, DW et al.. Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program. J Am Coll Cardiol. 2024;84 (3):247-257. doi: 10.1016/j.jacc.2024.04.038. PubMed PMID:38913004 .
  4. Verma, S, Butler, J, Borlaug, BA, Davies, M, Kitzman, DW, Shah, SJ et al.. Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials. J Am Coll Cardiol. 2024; :. doi: 10.1016/j.jacc.2024.06.001. PubMed PMID:38913003 .
  5. Kosiborod, MN, Cherney, D, Connelly, K, Desai, AS, Guimarães, PO, Kuthi, L et al.. Sodium Zirconium Cyclosilicate in HFrEF and Hyperkalemia: REALIZE-K Design and Baseline Characteristics. JACC Heart Fail. 2024; :. doi: 10.1016/j.jchf.2024.05.003. PubMed PMID:38878009 .
  6. Park, B, Krishnaraj, A, Teoh, H, Bakbak, E, Dennis, F, Quan, A et al.. GLP-1RA therapy increases circulating vascular regenerative cell content in people living with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2024;327 (2):H370-H376. doi: 10.1152/ajpheart.00257.2024. PubMed PMID:38874618 .
  7. Zhang, Q, Yaoita, N, Tabuchi, A, Liu, S, Chen, SH, Li, Q et al.. Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension. Circulation. 2024; :. doi: 10.1161/CIRCULATIONAHA.124.068726. PubMed PMID:38873770 .
  8. Krishnaraj, A, Dennis, F, Teoh, H, Verma, S, Hess, DA. Vascular regenerative cell content in South Asians: the key learnings. Curr Opin Cardiol. 2024; :. doi: 10.1097/HCO.0000000000001159. PubMed PMID:38847610 .
  9. An, KR, Sandner, S, Redfors, B, Alexander, JH, Alzghari, T, Caldonazo, T et al.. Association between overweight and obesity with coronary artery bypass graft failure: an individual patient data analysis of clinical trials. Eur J Cardiothorac Surg. 2024;65 (6):. doi: 10.1093/ejcts/ezae221. PubMed PMID:38830050 .
  10. Petrie, MC, Borlaug, BA, Butler, J, Davies, MJ, Kitzman, DW, Shah, SJ et al.. Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program. J Am Coll Cardiol. 2024;84 (1):27-40. doi: 10.1016/j.jacc.2024.04.022. PubMed PMID:38819334 .
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Affiliations & Other Activities

  • Cardiac Surgeon, Division of Cardiology , St. Michael’s Hospital
  • Professor of Surgery and Pharmacology & Toxicology, University of Toronto
  • Canada Research Chair in Cardiovascular Surgery